Peptide design and self-assembly into targeted nanostructure and functional materials

NJ Sinha, MG Langenstein, DJ Pochan… - Chemical …, 2021 - ACS Publications
Peptides have been extensively utilized to construct nanomaterials that display targeted
structure through hierarchical assembly. The self-assembly of both rationally designed …

A review of curcumin and its derivatives as anticancer agents

MA Tomeh, R Hadianamrei, X Zhao - International journal of molecular …, 2019 - mdpi.com
Cancer is the second leading cause of death in the world and one of the major public health
problems. Despite the great advances in cancer therapy, the incidence and mortality rates of …

Self-assembled peptide and protein nanostructures for anti-cancer therapy: Targeted delivery, stimuli-responsive devices and immunotherapy

M Delfi, R Sartorius, M Ashrafizadeh, E Sharifi, Y Zhang… - Nano Today, 2021 - Elsevier
Self-assembled peptides and proteins possess tremendous potential as targeted drug
delivery systems and key applications of these well-defined nanostructures reside in anti …

Personal perspective on understanding low molecular weight gels

DJ Adams - Journal of the American Chemical Society, 2022 - ACS Publications
Low molecular weight gels are formed by the self-assembly of small molecules into
anisotropic structures that form a network capable of immobilizing the solvent. Such gels are …

Designing hydrogels for controlled drug delivery

J Li, DJ Mooney - Nature Reviews Materials, 2016 - nature.com
Hydrogel delivery systems can leverage therapeutically beneficial outcomes of drug delivery
and have found clinical use. Hydrogels can provide spatial and temporal control over the …

Drug delivery by supramolecular design

MJ Webber, R Langer - Chemical Society Reviews, 2017 - pubs.rsc.org
The rational design of drug delivery approaches leveraging supramolecular chemistry
(ie,“chemistry beyond the molecule”) has garnered significant interest in recent years toward …

Recent advances of self-assembling peptide-based hydrogels for biomedical applications

J Li, R Xing, S Bai, X Yan - Soft matter, 2019 - pubs.rsc.org
Peptide-based hydrogels have been proven to be preeminent biomedical materials due to
their high water content, tunable mechanical stability, great biocompatibility and excellent …

Supramolecular hydrogelators and hydrogels: from soft matter to molecular biomaterials

X Du, J Zhou, J Shi, B Xu - Chemical reviews, 2015 - ACS Publications
In this review we intend to provide a relatively comprehensive summary of the work of
supramolecular hydrogelators after 2004 and to put emphasis particularly on the …

Supramolecular biomaterials

MJ Webber, EA Appel, EW Meijer, R Langer - Nature materials, 2016 - nature.com
Polymers, ceramics and metals have historically dominated the application of materials in
medicine. Yet rationally designed materials that exploit specific, directional, tunable and …

Design and applications of man-made biomimetic fibrillar hydrogels

E Prince, E Kumacheva - Nature Reviews Materials, 2019 - nature.com
Many extracellular matrices (ECMs) have a filamentous architecture, which influences cell
growth and phenotype and imparts tissues with specific properties. Man-made fibrillar …