DeepPhos: prediction of protein phosphorylation sites with deep learning
Motivation Phosphorylation is the most studied post-translational modification, which is
crucial for multiple biological processes. Recently, many efforts have been taken to develop …
crucial for multiple biological processes. Recently, many efforts have been taken to develop …
Recent advances in phosphoproteomics and application to neurological diseases
Phosphorylation has an incredible impact on the biological behavior of proteins, altering
everything from intrinsic activity to cellular localization and complex formation. It is no …
everything from intrinsic activity to cellular localization and complex formation. It is no …
Thirty years of molecular dynamics simulations on posttranslational modifications of proteins
Posttranslational modifications (PTMs) are an integral component to how cells respond to
perturbation. While experimental advances have enabled improved PTM identification …
perturbation. While experimental advances have enabled improved PTM identification …
Overexpression of MdCPK1a gene, a calcium dependent protein kinase in apple, increase tobacco cold tolerance via scavenging ROS accumulation
H Dong, C Wu, C Luo, M Wei, S Qu, S Wang - PLoS One, 2020 - journals.plos.org
Calcium-dependent protein kinases (CDPKs) are important calcium receptors, which play a
crucial part in the process of sensing and decoding intracellular calcium signals during plant …
crucial part in the process of sensing and decoding intracellular calcium signals during plant …
HIV envelope glycoform heterogeneity and localized diversity govern the initiation and maturation of a V2 apex broadly neutralizing antibody lineage
Understanding how broadly neutralizing antibodies (bnAbs) to HIV envelope (Env) develop
during natural infection can help guide the rational design of an HIV vaccine. Here, we …
during natural infection can help guide the rational design of an HIV vaccine. Here, we …
Identification and analysis of the N6-methyladenosine in the Saccharomyces cerevisiae transcriptome
Abstract Knowledge of the distribution of N6-methyladenosine (m6A) is invaluable for
understanding RNA biological functions. However, limitation in experimental methods …
understanding RNA biological functions. However, limitation in experimental methods …
Sulfoproteomics workflow with precursor ion accurate mass shift analysis reveals novel tyrosine sulfoproteins in the golgi
Tyrosine sulfation in the Golgi of secreted and membrane proteins is an important post-
translational modification (PTM). However, its labile nature has limited analysis by mass …
translational modification (PTM). However, its labile nature has limited analysis by mass …
A comprehensive catalog of the lysine-acetylation targets in rice (Oryza sativa) based on proteomic analyses
Y Xiong, X Peng, Z Cheng, W Liu, GL Wang - Journal of proteomics, 2016 - Elsevier
Lysine acetylation is a dynamic and reversible post-translational modification that plays an
important role in the gene transcription regulation. Here, we report high quality proteome …
important role in the gene transcription regulation. Here, we report high quality proteome …
A disordered acidic domain in GPIHBP1 harboring a sulfated tyrosine regulates lipoprotein lipase
KK Kristensen, SR Midtgaard… - Proceedings of the …, 2018 - National Acad Sciences
The intravascular processing of triglyceride-rich lipoproteins depends on lipoprotein lipase
(LPL) and GPIHBP1, a membrane protein of endothelial cells that binds LPL within the …
(LPL) and GPIHBP1, a membrane protein of endothelial cells that binds LPL within the …
Suberoylanilide hydroxamic acid treatment reveals crosstalks among proteome, ubiquitylome and acetylome in non-small cell lung cancer A549 cell line
Q Wu, Z Cheng, J Zhu, W Xu, X Peng, C Chen, W Li… - Scientific reports, 2015 - nature.com
Suberoylanilide hydroxamic acid (SAHA) is a well-known histone deacetylase (HDAC)
inhibitor and has been used as practical therapy for breast cancer and non-small cell lung …
inhibitor and has been used as practical therapy for breast cancer and non-small cell lung …