Ursolic and oleanolic acids are secondary plant metabolites that are known to be involved in
the plant defence system against water loss and pathogens. Nowadays these triterpenoids …

Natural pentacyclic triterpenoids (PTs) have been often reported to exhibit a wide range of
biological activities. Among them, the anticancer and anti-inflammatory activities are the …

Discovery of bioactive molecules and elucidation of their molecular mechanisms open up an
enormous opportunity for the development of improved therapy for different inflammatory …

Covering: up to 2014 In silico approaches have been widely recognised to be useful for drug
discovery. Here, we consider the significance of available databases of medicinal plants and …

Background: Ursolic acid (UA) is a natural pentacyclic triterpene derived from fruit, herb, and
other plants. UA can act on molecular targets of various signaling pathways, inhibit the …

Breast cancer is the second leading cause of death from cancer in women in the United
States. A growing emphasis is being placed on alternative medicine and dietary approaches …

Ursolic acid (UA) is a pentacyclic triterpenoid frequently found in medicinal herbs and plants,
having numerous pharmacological effects. UA and its analogs treat multiple diseases …

Methoxyestradiol (2ME2) is an investigational anticancer drug. In the present study, 2-
alkoxyesters/acid and 2-benzyloxy analogues of estradiol have been synthesized as …

Lung cancer is the leading cause of cancer-related deaths globally. Despite current
treatment approaches that include surgery, chemotherapy, radiation and immunotherapies …

Asiatic acid (AA) derivatives 4 and 5 modified at the C-11 and C-28 positions were designed
and synthesized, their structures were confirmed using HRMS, 1 H NMR and 13 C NMR. In …