Acute stroke biomarkers: are we there yet?
M Dagonnier, GA Donnan, SM Davis… - Frontiers in …, 2021 - frontiersin.org
Background: Distinguishing between stroke subtypes and knowing the time of stroke onset
are critical in clinical practice. Thrombolysis and thrombectomy are very effective treatments …
are critical in clinical practice. Thrombolysis and thrombectomy are very effective treatments …
Blood biomarkers for stroke diagnosis and management
J Kamtchum-Tatuene, GC Jickling - Neuromolecular medicine, 2019 - Springer
Biomarkers are objective indicators used to assess normal or pathological processes,
evaluate responses to treatment and predict outcomes. Many blood biomarkers already …
evaluate responses to treatment and predict outcomes. Many blood biomarkers already …
Association of ischemic stroke onset time with presenting severity, acute progression, and long-term outcome: a cohort study
Background Preclinical data suggest circadian variation in ischemic stroke progression, with
more active cell death and infarct growth in rodent models with inactive phase (daytime) …
more active cell death and infarct growth in rodent models with inactive phase (daytime) …
Inflammatory markers and poor outcome after stroke: a prospective cohort study and systematic review of interleukin-6
Background The objective of this study was to determine whether:(a) markers of acute
inflammation (white cell count, glucose, interleukin-6, C-reactive protein, and fibrinogen) are …
inflammation (white cell count, glucose, interleukin-6, C-reactive protein, and fibrinogen) are …
[HTML][HTML] Blood biomarkers of ischemic stroke
GC Jickling, FR Sharp - Neurotherapeutics, 2011 - Elsevier
This review provides a summary of the protein and RNA biomarkers that have been studied
for the diagnosis and assessment of ischemic stroke. Many of the biomarkers identified …
for the diagnosis and assessment of ischemic stroke. Many of the biomarkers identified …
Progressive lacunar stroke: review of mechanisms, prognostic features, and putative treatments
A Del Bene, V Palumbo, M Lamassa… - … Journal of Stroke, 2012 - journals.sagepub.com
Lacunar stroke is generally considered to have a fair outcome. However 20–30% of patients
with lacunar stroke worsen neurologically in hours or days after onset, reaching eventually …
with lacunar stroke worsen neurologically in hours or days after onset, reaching eventually …
Biomarkers and the outcomes of ischemic stroke
Y Huang, Z Wang, ZX Huang, Z Liu - Frontiers in Molecular …, 2023 - frontiersin.org
Biomarkers are measurable substances that could be used as objective indicators for
disease diagnosis, responses to treatments, and outcomes predictions. In this review, we …
disease diagnosis, responses to treatments, and outcomes predictions. In this review, we …
[HTML][HTML] Blood/brain biomarkers of inflammation after stroke and their association with outcome: from C-reactive protein to damage-associated molecular patterns
A Bustamante, A Simats, A Vilar-Bergua… - …, 2016 - Elsevier
Stroke represents one of the most important causes of disability and death in developed
countries. However, there is a lack of prognostic tools in clinical practice to monitor the …
countries. However, there is a lack of prognostic tools in clinical practice to monitor the …
Glial cell AMPA receptors in nervous system health, injury and disease
M Ceprian, D Fulton - International journal of molecular sciences, 2019 - mdpi.com
Glia form a central component of the nervous system whose varied activities sustain an
environment that is optimised for healthy development and neuronal function. Alpha-amino …
environment that is optimised for healthy development and neuronal function. Alpha-amino …
[HTML][HTML] GC–MS-based metabolomics identifies an amino acid signature of acute ischemic stroke
D Wang, J Kong, J Wu, X Wang, M Lai - Neuroscience Letters, 2017 - Elsevier
Ischemic stroke is a serious public health problem worldwide. Here, we characterized the
metabolite features of acute ischemic stroke (AIS) using a gas chromatography-mass …
metabolite features of acute ischemic stroke (AIS) using a gas chromatography-mass …