Mast cells are hematopoietic cells that reside in virtually all vascularized tissues and that
represent potential sources of a wide variety of biologically active secreted products …

Prolonged low-grade inflammation or smoldering inflammation is a hallmark of cancer. Mast
cells form a heterogeneous population of immune cells with differences in their ultra …

Mast cells (MC) are widely distributed throughout the body and are common at mucosal
surfaces, a major host–environment interface. MC are functionally and phenotypically …

Mast cells and basophils are key contributors to allergies and other inflammatory diseases
since they are the most prominent source of histamine as well as numerous additional …

Although IgE binding to mast cells is thought to be a passive presensitization step, we
demonstrate herein that monomeric IgE (mIgE) in the absence of antigen (Ag) stimulates …

Patients with clonal mast cell activation syndromes (MCAS) including cutaneous and
systemic mastocytosis (SM) may present with symptoms of mast cell activation, but in …

Mast cells are critical players in allergic reactions, but they have also been shown to be
important in immunity and recently also in inflammatory diseases, especially asthma …

Mast cells are immune cells which have a widespread distribution in nearly all tissues.
These cells and their mediators are canonically viewed as primary effector cells in allergic …

Kit is a receptor tyrosine kinase (RTK) that binds stem cell factor. This receptor ligand
combination is important for normal hematopoiesis, as well as pigmentation, gut function …

Several inflammatory skin conditions, including atopic dermatitis (AD) and psoriasis, are
exacerbated by stress. Recent evidence suggests that crosstalk between mast cells …