Role of Wnt/β‐Catenin Signaling in the Chemoresistance Modulation of Colorectal Cancer

S Yuan, F Tao, X Zhang, Y Zhang… - BioMed research …, 2020 - Wiley Online Library
Colorectal cancer (CRC) is a common malignancy with high morbidity and mortality
worldwide. To date, chemotherapy plays an important role in the treatment of CRC patients …

Therapeutic strategies targeting Wnt/β‑catenin signaling for colorectal cancer

Y Ji, J Lv, D Sun, Y Huang - … journal of molecular …, 2022 - spandidos-publications.com
Colorectal cancer (CRC) is one of the most common carcinomas. Although great progress
has been made in recent years, CRC survival remains unsatisfactory due to high metastasis …

Wound-Healing Potential of Rhoifolin-Rich Fraction Isolated from Sanguisorba officinalis Roots Supported by Enhancing Re-Epithelization, Angiogenesis, Anti …

WA Negm, AH El-Kadem, E Elekhnawy, NGM Attallah… - Pharmaceuticals, 2022 - mdpi.com
A wound is a complicated bioprocess resulting in significant tissue damage, which is
worsened by a secondary bacterial infection, commonly Pseudomonas aeruginosa and …

Targeting regulated cell death with plant natural compounds for cancer therapy: A revisited review of apoptosis, autophagy‐dependent cell death, and necroptosis

Y Yang, Y Chen, JH Wu, Y Ren, B Liu… - Phytotherapy …, 2023 - Wiley Online Library
Regulated cell death (RCD) refers to programmed cell death regulated by various protein
molecules, such as apoptosis, autophagy‐dependent cell death, and necroptosis …

Evaluation of Polyphenolic Composition and Antimicrobial Properties of Sanguisorba officinalis L. and Sanguisorba minor Scop.

AC Tocai, F Ranga, AG Teodorescu, A Pallag, AM Vlad… - Plants, 2022 - mdpi.com
The most widespread Sanguisorba species are Sanguisorba officinalis L. and Sanguisorba
minor Scop. which are also found in the Romanian flora and classified as medicinal plants …

Therapeutic potential of naturally occurring small molecules to target the wnt/β-catenin signaling pathway in colorectal cancer

LFS Oliveira, D Predes, HL Borges, JG Abreu - Cancers, 2022 - mdpi.com
Simple Summary Colorectal cancer (CRC) is an emerging public health problem and the
second leading cause of death worldwide, with a significant socioeconomic impact in …

Tannic acid promotes TRAIL-induced extrinsic apoptosis by regulating mitochondrial ROS in human embryonic carcinoma cells

N Sp, DY Kang, ES Jo, A Rugamba, WS Kim, YM Park… - Cells, 2020 - mdpi.com
Human embryonic carcinoma (EC; NCCIT) cells have self-renewal ability and pluripotency.
Cancer stem cell markers are highly expressed in NCCIT cells, imparting them with the …

Network Pharmacology and Pharmacological Evaluation Reveals the Mechanism of the Sanguisorba Officinalis in Suppressing Hepatocellular Carcinoma

N Jiang, H Li, Y Sun, J Zeng, F Yang… - Frontiers in …, 2021 - frontiersin.org
Background: Sanguisorba Officinalis L.(SO) is a well-known traditional Chinese medicine
(TCM), commonly applied to treat complex diseases, such as anticancer, antibacterial …

Sanguisorba officinalis L. derived from herbal medicine prevents intestinal inflammation by inducing autophagy in macrophages

A Yasueda, H Kayama, M Murohashi, J Nishimura… - Scientific reports, 2020 - nature.com
Disturbed activation of autophagy is implicated in the pathogenesis of inflammatory bowel
disease. Accordingly, several autophagy-related genes have been identified as Crohn's …

Hypotensive and Vasorelaxant Effects of Sanguisorbae Radix Ethanol Extract in Spontaneously Hypertensive and Sprague Dawley Rats

J Jung, S Shin, J Park, K Lee, HY Choi - Nutrients, 2023 - mdpi.com
Hypertension requires proper management because of the increased risk of cardiovascular
disease and death. For this purpose, functional foods containing tannins have been …