Emerging roles of the RNA modifications N6-methyladenosine and adenosine-to-inosine in cardiovascular diseases
V Sikorski, A Vento, E Kankuri - Molecular Therapy-Nucleic Acids, 2022 - cell.com
Cardiovascular diseases lead the mortality and morbidity disease metrics worldwide. A
multitude of chemical base modifications in ribonucleic acids (RNAs) have been linked with …
multitude of chemical base modifications in ribonucleic acids (RNAs) have been linked with …
Lessons learned and yet-to-Be learned on the importance of RNA structure in SARS-CoV-2 replication
SUMMARY SARS-CoV-2, the etiological agent responsible for the COVID-19 pandemic, is a
member of the virus family Coronaviridae, known for relatively extensive (~ 30-kb) RNA …
member of the virus family Coronaviridae, known for relatively extensive (~ 30-kb) RNA …
2′-O-methylation at internal sites on mRNA promotes mRNA stability
O-methylation (Nm) is a prominent RNA modification well known in noncoding RNAs and
more recently also found at many mRNA internal sites. However, their function and base …
more recently also found at many mRNA internal sites. However, their function and base …
RODAN: a fully convolutional architecture for basecalling nanopore RNA sequencing data
Background Despite recent progress in basecalling of Oxford nanopore DNA sequencing
data, its wide adoption is still being hampered by its relatively low accuracy compared to …
data, its wide adoption is still being hampered by its relatively low accuracy compared to …
[HTML][HTML] Microbiome-induced reprogramming in post-transcriptional landscape using nanopore direct RNA sequencing
It has been widely recognized that the microbiota has the capacity to shape host gene
expression and physiological functions. However, there remains a paucity of comprehensive …
expression and physiological functions. However, there remains a paucity of comprehensive …
Mitochondrial transcriptome of Candida albicans in flagranti — direct RNA sequencing reveals a new layer of information
Background Organellar transcriptomes are relatively under-studied systems, with data
related to full-length transcripts and posttranscriptional modifications remaining sparse …
related to full-length transcripts and posttranscriptional modifications remaining sparse …
It's the little things (in viral RNA)
JF Potužník, H Cahová - MBio, 2020 - Am Soc Microbiol
Chemical modifications of viral RNA are an integral part of the viral life cycle and are present
in most classes of viruses. To date, more than 170 RNA modifications have been discovered …
in most classes of viruses. To date, more than 170 RNA modifications have been discovered …
Deciphering transcript architectural complexity in bacteria and archaea
ABSTRACT RNA transcripts are potential therapeutic targets, yet bacterial transcripts have
uncharacterized biodiversity. We developed an algorithm for transcript prediction called tp …
uncharacterized biodiversity. We developed an algorithm for transcript prediction called tp …
nanoDoc: RNA modification detection using Nanopore raw reads with Deep One-Class Classification
H Ueda - bioRxiv, 2020 - biorxiv.org
Advances in Nanopore single-molecule direct RNA sequencing (DRS) have presented the
possibility of detecting comprehensive post-transcriptional modifications (PTMs) as an …
possibility of detecting comprehensive post-transcriptional modifications (PTMs) as an …
RNA Modification Detection Using Nanopore Direct RNA Sequencing and nanoDoc2
H Ueda, B Dasgupta, B Yu - Nanopore Sequencing: Methods and …, 2023 - Springer
RNA modifications regulate multiple aspects of cellular function including RNA splicing,
translation, export, decay, stability, and phase separation. One of the comprehensive ways …
translation, export, decay, stability, and phase separation. One of the comprehensive ways …