Cancer stem cells (CSC) theory has ushered in a new era of cancer research. Tumor
recurrence, metastasis and chemotherapy resistance are all related to the existence of …

Hepatocellular carcinoma (HCC) is the fifth most commonly diagnosed type of cancer. The
tumor inflammatory microenvironment regulates almost every step towards liver …

End-stage liver disease and liver failure are major health problems worldwide leading to
high mortality and morbidity and high healthcare costs. Currently, orthotropic liver …

Background: It is difficult to prospectively identify and maintain putative tumor-initiating cells
(TICs). Spheres that formed in serum-free media contained more TICs while spheres formed …

The liver has a tremendous capacity to regenerate at all developmental stages (for reviews,
see (1-3)). Liver cell mass can be restored even after repeated partial hepatectomies as well …

Cell therapy represents a promising alternative strategy for end‐stage liver disease, and
hepatic progenitors are the best candidates. The possibility to maximize the paracrine effects …

The liver is well-known for its ability to regenerate in response to damage. While little is
known about the precise molecular mechanism governing liver regeneration, much research …

0344 3 Human_Mongardini.ps, page 1-4 @ Normalize ( 0344 3 Human_Mongardini:- ) Page
1 Introduction Faecal incontinence is a clinical condition that can have devastating social …