Highlights•Work on circadian period determination and output gene regulation are
reviewed.•Clock protein glycosylation, ubiquitylation and translation influence 24 hours …

Highlights•The Drosophila circadian pacemaker consists of transcriptional feedback
loops.•Cascades of protein phosphorylation/dephosphorylation determine period …

For many years, a connection between circadian clocks and cancer has been postulated.
Here we describe an unexpected function for the circadian repressor CRY2 as a component …

In many vertebrate and invertebrate organisms, gametes develop within groups of
interconnected cells called germline cysts formed by several rounds of incomplete divisions …

Circadian timekeeping is a ubiquitous mechanism that enables organisms to maintain
temporal coordination between internal biological processes and time of the local …

ZEITLUPE (ZTL), a photoreceptor with E3 ubiquitin ligase activity, communicates end-of-day
light conditions to the plant circadian clock. It still remains unclear how ZTL protein …

Circadian rhythms, endogenous cycles of about 24 h in physiology, are generated by a
master clock located in the suprachiasmatic nucleus of the hypothalamus and other clocks …

Circadian clocks are internal timing systems that enable organisms to adjust their behavioral
and physiological rhythms to the daily changes of their environment. These clocks generate …

Circadian clocks respond to temperature changes over the calendar year, allowing
organisms to adjust their daily biological rhythms to optimize health and fitness. In …

Many biological and behavioural processes of animals are governed by an endogenous
circadian clock, which is dependent on transcriptional regulation. Here we address post …