Within this review, sex-specific differences in alveolar epithelial functions are discussed with
special focus on preterm infants and the respiratory disorders associated with premature …

The fatal outcomes of COVID-19 are related to the high reactivity of the innate wing of
immunity. Estrogens could exert anti-inflammatory effects during SARS-CoV-2 infection at …

Na+/K+-ATPase, a plasma membrane protein abundantly expressed in epithelial tissues,
has been identified and linked to numerous biological events, including ion transport and …

Preterm infants frequently suffer from pulmonary complications due to a physiological and
structural lung immaturity resulting in significant morbidity and mortality. Novel in vitro and in …

Respiratory distress syndrome (RDS) is the most frequent pulmonary complication in
preterm infants. RDS incidence differs between genders, which has been called the male …

Background Epidemiologic data from studies of airway diseases, such as asthma, chronic
obstructive pulmonary disease, and cystic fibrosis indicate a gender disparity where women …

Background 17β-estradiol can suppress acute lung injury (ALI) and regulate alveolar
epithelial sodium channel (ENaC). However the relationship between these two functions …

Female sex predisposes individuals to poorer outcomes during respiratory disorders like
cystic fibrosis and influenza-associated pneumonia. A common link between these disorders …

The epithelium lining the female reproductive tract forms a selectively permeable barrier that
is responsible for creating an optimal luminal fluid microenvironment essential to the …

Cystic fibrosis (CF) is the most frequent inherited disease in Caucasian populations and is
due to a defect in the expression or activity of a chloride channel encoded by the cystic …