Understanding the function of biological macromolecules and their complexes at the
physicochemical level requires knowledge of both their structure and dynamics …

The phosphoenolpyruvate (PEP): carbohydrate phosphotransferase system (PTS) is found
only in bacteria, where it catalyzes the transport and phosphorylation of numerous …

Scientists in such fields as mathematics, physics, chemistry, biochemistry, biology, and
medicine are currently involved in investigations of porphyrins and their numerous …

▪ Abstract During the past thirty years, deuterium labeling has been used to improve the
resolution and sensitivity of protein NMR spectra used in a wide variety of applications. Most …

Highlights•Methyl-specific labeling for solution NMR studies of proteins above 100
kDa.•Specific labeling of any combination of methyl groups in protein overexpressed in E …

Our knowledge of biological macromolecules and their interactions is based on the
application of physical methods, ranging from classical thermodynamics to recently …

MARS a program for robust automatic backbone assignment of 13 C/15 N labeled proteins
is presented. MARS does not require tight thresholds for establishing sequential connectivity …

Recent advances in multidimensional NMR methodology to obtain 1 H, 15 N and 13 C
resonance assignments, interproton-distance and torsion-angle restraints, and restraints that …

It has recently been shown that the degree of alignment of macromolecules in an aqueous
dilute liquid crystalline medium of bicelles is sufficient to permit accurate values of residual …

The development of novel isotope labeling strategies for proteins has facilitated the study of
the structure and dynamics of these molecules. In addition, the recent emergence of …