Non-compressible torso hemorrhage (NCTH) is associated with significant mortality in
preventable deaths, both in the field and in civilian settings. Current management strategies …

Although 0.9% NaCl solution is by far the most-used fluid for fluid therapy in resuscitation, it
is difficult to find a paper advocating its use over other types of crystalloid solutions …

Background Restoration of brain tissue perfusion is a determining factor in the neurological
evolution of patients with traumatic brain injury (TBI) and hemorrhagic shock (HS). In a …

BACKGROUND Although minimization of crystalloids is a widely adopted practice in the
resuscitation of patients with severe hemorrhage, its direct impact on high-ratio resuscitation …

Objectives Prehospital transfusion can be life-saving when transport is delayed but
conventional plasma, red cells, and whole blood are often unavailable out of hospital. Shelf …

BACKGROUND Dried plasmas can overcome logistical barriers that prevent fresh frozen
plasma (FFP) usage in acute resuscitation, but processing of these products can …

Background: Voluven (hydroxyethyl starch [HES] 130/0.4), a new generation of HES product
with low molecular weight, has been widely used for the treatment of traumatic and …

Conclusion Component therapy is useful for the majority of patients when blood
requirements are minimal and there is no associated coagulopathy. Of concern are …

Objective: To test our hypothesis that hemoglobin-based oxygen carrier (HBOC)-201
resuscitation in hemorrhagic shock (HS) will not lead to increased organ injury and …

BACKGROUND Fluid replacement with blood products, colloids and crystalloids is
associated with morbidity and mortality. Despite this, the consequences of fluid …