Most of the cell's chemical reactions and structural components are facilitated by proteins.
But proteins are highly dynamic molecules, where numerous modifications or changes in the …

The complex symbiotic relationship between inflammation, the gut microbiota, and the
central nervous system (CNS) has become a pivotal focus of contemporary biomedical …

Neurodegenerative diseases, notably Alzheimer's and Parkinson's, hallmark their
progression through the formation of amyloid aggregates resulting from misfolding. While …

Soluble cytotoxic oligomers produced during the fibrillation of both α-synuclein (αS) and
amyloid-β protein (Aβ) are key pathogenic factors in Parkinson's disease (PD) and …

Background: Alzheimer's disease (AD) is an age-related degenerative change of the central
nervous system, the cause of which remains unclear. Recent studies have found that brain …

Human islet amyloid polypeptide (amylin or hIAPP) is a 37 residue hormone co‐secreted
with insulin from β cells of the pancreas. In patients suffering from type‐2 diabetes, amylin …

Although microbiology and neurology are separate disciplines, they are linked to some
infectious and neurological diseases. Today, microbiome is considered as one of the …

Alzheimer's disease (AD) is a progressive and largely incurable neurodegenerative disorder
that affects millions of people worldwide. It is characterised by the accumulation of amyloid …

Protein conformation is affected by interaction of several small molecules resulting either
stabilization or disruption depending on the nature of the molecules. In our earlier …