Managing the care of patients receiving antiresorptive therapy for prevention and treatment of osteoporosis: executive summary of recommendations from the …

JW Hellstein, RA Adler, B Edwards… - The Journal of the …, 2011 - Elsevier
Background This narrative review of osteonecrosis of the jaw in patients with low bone mass
receiving treatment with antiresorptive agents is based on an appraisal of the literature by an …

Preclinical models of medication-related osteonecrosis of the jaw (MRONJ)

JI Aguirre, EJ Castillo, DB Kimmel - Bone, 2021 - Elsevier
Medication-related osteonecrosis of the jaw (MRONJ) is a potentially severe adverse event
affecting patients with cancer and patients with osteoporosis who have been treated with …

Oncologic doses of zoledronic acid induce osteonecrosis of the jaw‐like lesions in rice rats (Oryzomys palustris) with periodontitis

JI Aguirre, MP Akhter, DB Kimmel… - Journal of Bone and …, 2012 - academic.oup.com
Though osteonecrosis of the jaw (ONJ) is temporally‐associated with the use of nitrogen‐
containing bisphosphonates (N‐BPs), a cause‐and‐effect relationship has not yet been …

Medication‐related osteonecrosis of the jaw: a literature review and update

S Kuroshima, FA Al‐Omari, M Sasaki, T Sawase - Genesis, 2022 - Wiley Online Library
Since the initial description of medication‐related osteonecrosis of the jaw (MRONJ) almost
two decades ago, the potential pathophysiology and risk factors have been elaborated on in …

Antiresorptives and osteonecrosis of the jaw

J Yamashita, LK McCauley - Journal of Evidence Based Dental Practice, 2012 - Elsevier
Osteonecrosis of the jaw (ONJ) is an uncommon condition noted to occur in patients who are
receiving osteoclast-targeted antiresorptive therapy. The incidence of ONJ in patients taking …

Maresin 1 promotes wound healing and socket bone regeneration for alveolar ridge preservation

CW Wang, SH Yu, T Fretwurst… - Journal of dental …, 2020 - journals.sagepub.com
Tooth extraction results in alveolar bone resorption and is accompanied by postoperative
swelling and pain. Maresin 1 (MaR1) is a proresolving lipid mediator produced by …

Zoledronic acid–related osteonecrosis of the jaws. Experimental model with dental extractions in rats

P Barba-Recreo, M García-Arranz, L Yébenes… - Journal of Cranio …, 2014 - Elsevier
Introduction Bisphosphonate-related osteonecrosis of the jaws (BRONJ) is a pathologic
condition of increasing frequency, with a poorly understood pathophysiology and which can …

The Saxon Bisphosphonate Register–Therapy and prevention of bisphosphonate-related osteonecrosis of the jaws

M Schubert, I Klatte, W Linek, B Müller, K Döring… - Oral oncology, 2012 - Elsevier
In 2009, a study group of three Saxon hospitals set up a Saxon register with the aim of
including all patients with bisphosphonate (BP) medication. In addition, specific concepts for …

[HTML][HTML] Bisphosphonate-related osteonecrosis of the jaw: a mechanobiology perspective

EL George, YL Lin, MM Saunders - Bone Reports, 2018 - Elsevier
Bisphosphonate-related osteonecrosis of the jaw (BRONJ) is a dramatic disintegration of the
jaw that affects patients treated with bisphosphonates (BPs) for diseases characterized by …

Systemic administration of omeprazole interferes with bone healing and implant osseointegration: an in vivo study on rat tibiae

A Al Subaie, E Emami, I Tamimi… - Journal of clinical …, 2016 - Wiley Online Library
Background Proton pump inhibitors, over‐the‐counter drugs taken by millions of patients,
diminish bone accrual. Accordingly, we hypothesized that these drugs could impair bone …