An overview of topic modeling and its current applications in bioinformatics

L Liu, L Tang, W Dong, S Yao, W Zhou - SpringerPlus, 2016 - Springer
Background With the rapid accumulation of biological datasets, machine learning methods
designed to automate data analysis are urgently needed. In recent years, so-called topic …

Identifying miRNAs, targets and functions

B Liu, J Li, MJ Cairns - Briefings in bioinformatics, 2014 - academic.oup.com
Abstract microRNAs (miRNAs) are small endogenous non-coding RNAs that function as the
universal specificity factors in post-transcriptional gene silencing. Discovering miRNAs …

Latent Dirichlet allocation (LDA) and topic modeling: models, applications, a survey

H Jelodar, Y Wang, C Yuan, X Feng, X Jiang… - Multimedia tools and …, 2019 - Springer
Topic modeling is one of the most powerful techniques in text mining for data mining, latent
data discovery, and finding relationships among data and text documents. Researchers …

A network approach to topic models

M Gerlach, TP Peixoto, EG Altmann - Science advances, 2018 - science.org
One of the main computational and scientific challenges in the modern age is to extract
useful information from unstructured texts. Topic models are one popular machine-learning …

MicroRNA regulons in tumor microenvironment

HI Suzuki, A Katsura, H Matsuyama, K Miyazono - Oncogene, 2015 - nature.com
Cancer initiation and progression are defined by the behavior of cancer cells per se and the
development of tumor tissues, both of which are modulated by crosstalk between cancer …

Evaluation of clustering and topic modeling methods over health-related tweets and emails

JA Lossio-Ventura, S Gonzales, J Morzan… - Artificial intelligence in …, 2021 - Elsevier
Background Internet provides different tools for communicating with patients, such as social
media (eg, Twitter) and email platforms. These platforms provided new data sources to shed …

Identification of microRNA-regulated gene networks by expression analysis of target genes

VA Gennarino, G d'Angelo, G Dharmalingam… - Genome …, 2012 - genome.cshlp.org
MicroRNAs (miRNAs) and transcription factors control eukaryotic cell proliferation,
differentiation, and metabolism through their specific gene regulatory networks. However …

High-reproducibility and high-accuracy method for automated topic classification

A Lancichinetti, MI Sirer, JX Wang, D Acuna, K Körding… - Physical Review X, 2015 - APS
Much of human knowledge sits in large databases of unstructured text. Leveraging this
knowledge requires algorithms that extract and record metadata on unstructured text …

[HTML][HTML] MicroRNA-296-5p (miR-296-5p) functions as a tumor suppressor in prostate cancer by directly targeting Pin1

KH Lee, FC Lin, TI Hsu, JT Lin, JH Guo, CH Tsai… - … et Biophysica Acta (BBA …, 2014 - Elsevier
Upregulation of Pin1 was shown to advance the functioning of several oncogenic pathways.
It was recently shown that Pin1 is potentially an excellent prognostic marker and can also …

Topic model-based recommender systems and their applications to cold-start problems

M Kawai, H Sato, T Shiohama - Expert Systems with Applications, 2022 - Elsevier
Recommender systems provide information and items that match a user's preference. This
study proposes hybrid recommender models that use content-based filtering and latent …