Objective Polypharmacy has been linked to a myriad of adverse consequences, and
escalating rates of polypharmacy present an emerging concern, particularly among older …

Abstract Purpose Drug-drug interactions (DDIs) are often avoidable and, if undetected, can
lead to patient harm. This review aimed to determine the prevalence of potential DDIs …

Purpose To determine risk factors for each severity-based category of potential drug-drug
interactions (DDIs) encountered at intensive care unit (ICU) patients. Methods This was a …

Objective: The association between polypharmacy and dementia is controversial. This
systematic review and meta-analysis aims to summarize existing literature concerning the …

Background Polypharmacy is associated with adverse events and multimorbidity, but data
are limited on its association with specific comorbidities in primary care settings. We …

Abstract Background Drug interactions (DIs) are a significant cause of medication-related
problems. The aging population, high chronic diseases prevalence and polypharmacy are …

According to the World Health Report 2000, health system responsiveness is proposed as
one of the three key objectives of any health system. This multi-domain concept describes …

We studied the association between multimorbidity, polypharmacy, and mortality in 1,050
older adults (50+) with intellectual disability (ID). Multimorbidity (presence of≥ 4 chronic …

Background Diltiazem, a moderate cytochrome P450 3A4 isozyme/P‐glycoprotein inhibitor,
may potentiate the bleeding risk of direct oral anticoagulants (DOACs) through …

Chronic hepatitis C virus (HCV) infection is common among patients with chronic kidney
disease (CKD) and those on hemodialysis due to nosocomial infections and past blood …