Our understanding of diabetes mellitus has benefited from a combination of clinical
investigations and work in model organisms and cell lines. Organoid models for a wide …

Organoids have become one of the fastest progressing and applied models in biological
and medical research, and various organoids have now been developed for most of the …

In vitro derivation of pancreatic β-cells from human pluripotent stem cells holds promise as
diabetes treatment. Despite recent progress, efforts to generate physiologically competent β …

Diabetes is a complex metabolic disease characterized by chronic hyperglycemia and
categorized into two types: insulino-dependent (Type 1, T1D) and non-insulino-dependent …

Insulin-dependent diabetes mellitus or type 1 diabetes mellitus (T1DM) is an auto-immune
condition characterized by the loss of pancreatic β-cells. The curative approach for highly …

Abstract Ginseng peptide (GP)(100, 200, 400 mg/kg bw) lowered blood glucose levels,
explored the relationship between GP and gut microbiota-based hypoglycemic effects. GP …

Bioengineered pancreatic β-islets have been widely advocated for the research and
treatment of diabetes by offering both suitable cell culture models for the study of the …

Unraveling molecular and functional heterogeneity of niche cells within the developing
endoderm could resolve mechanisms of tissue formation and maturation. Here, we discuss …