In 2005, two tetanus toxoid, reduced diphtheria toxoid, and acellular pertussis (Tdap)
vaccines were licensed and recommended for use in adults and adolescents in the United …

Vaccination during pregnancy results in an augmentation of disease specific maternal
antibodies. Immunoglobulin G (IgG) is mainly transferred through the placenta during the …

In several prior articles I have attempted to analyze and simplify the subject of
immunological functions induced by vaccination that correlate with protection against later …

Abstract (See the Editorial Commentary by Munoz and Englund, on pages 893–6.)
Background. Because adolescents and adults act as a primary source of pertussis infection …

OBJECTIVES: To evaluate the safety and immunogenicity of an additional birth dose of
diphtheria, tetanus, and acellular pertussis vaccine (DTaP). STUDY DESIGN: Fifty infants …

Vaccination of pregnant women is recommended for some infectious diseases in order to
protect both women and offspring through high titres of maternal IgG antibodies. Less is …

Vaccinology has come a long way from early, empirically developed vaccines to modern
vaccines rationally designed and produced. Vaccines are meant to cooperate with the …

The recent immunological investigations, stemming from the studies performed in the
nineties within the clinical trials of the acellular pertussis vaccines, have highlighted the …

Background Pertussis is frequently reported to be more common in females than in males.
However, the variability of the sources of these observations makes it difficult to estimate the …

Pertussis, caused by Bordetella (B.) pertussis, a Gram-negative bacterium, is a highly
contagious airway infection. Especially in infants, pertussis remains a major health concern …