Adipocyte inflammation is the primary driver of hepatic insulin resistance in a human iPSC-based microphysiological system

L Qi, M Groeger, A Sharma, I Goswami, E Chen… - Nature …, 2024 - nature.com
Interactions between adipose tissue, liver and immune system are at the center of metabolic
dysfunction-associated steatotic liver disease and type 2 diabetes. To address the need for …

A Novel Foodstuff Mixture Improves the Gut–Liver Axis in MASLD Mice and the Gut Microbiota in Overweight/Obese Patients

R Rosas-Campos, AS Sandoval-Rodríguez… - Antioxidants, 2024 - mdpi.com
Microbial community control is crucial for maintaining homeostasis of the gut–liver axis in
metabolic dysfunction-associated steatotic liver disease (MASLD). Here, we show that …

Unveiling nuclear chromatin distribution using IsoConcentraChromJ: A flourescence imaging plugin for IsoRegional and IsoVolumetric based ratios analysis

L Zeaiter, A Dabbous, F Baldini, A Pagano, P Bianchini… - Plos one, 2024 - journals.plos.org
Chromatin exhibits non-random distribution within the nucleus being arranged into discrete
domains that are spatially organized throughout the nuclear space. Both the spatial …