[HTML][HTML] Targeting macrophages in hematological malignancies: recent advances and future directions
Emerging evidence indicates that the detection and clearance of cancer cells via
phagocytosis induced by innate immune checkpoints play significant roles in tumor …
phagocytosis induced by innate immune checkpoints play significant roles in tumor …
CD47‐SIRPα blocking‐based immunotherapy: Current and prospective therapeutic strategies
R Bouwstra, T van Meerten… - Clinical and Translational …, 2022 - Wiley Online Library
Background The CD47‐signal regulatory protein alpha (SIRPα)'don't eat me'signalling axis
is perhaps the most prominent innate immune checkpoint to date. However, from initial …
is perhaps the most prominent innate immune checkpoint to date. However, from initial …
[HTML][HTML] Regulation of B-cell receptor signaling and its therapeutic relevance in aggressive B-cell lymphomas
Simple Summary Dysregulated B-cell receptor (BCR) signaling is considered a potent
contributor to tumor survival in different subtypes of B-cell non-Hodgkin lymphomas (B …
contributor to tumor survival in different subtypes of B-cell non-Hodgkin lymphomas (B …
[HTML][HTML] Macrophage-Based Therapeutic Strategies in Hematologic Malignancies
Simple Summary Tumor-associated macrophages (TAMs) are the most prevalent
immunosuppressive myeloid cells in the tumor microenvironment, playing significant …
immunosuppressive myeloid cells in the tumor microenvironment, playing significant …
[PDF][PDF] The role of CD47 in non-neoplastic diseases
C Wang, Y Feng, D Patel, H Xie, Y Lv, H Zhao - Heliyon, 2023 - cell.com
CD47 is a 50 kDa five-spanning membrane receptor that plays a crucial role in multiple
cellular processes, including myeloid cell activation, neutrophils transmigration, vascular …
cellular processes, including myeloid cell activation, neutrophils transmigration, vascular …
The Non-hodgkin Lymphoma Treatment and Side Effects: A Systematic Review and Meta-analysis
AB Câmara, IA Brandão - Recent Patents on Anti-Cancer Drug …, 2024 - ingentaconnect.com
Objectives: This paper aims to review studies regarding side effects found during Non-
Hodgkin Lymphoma treatment, to suggest the drug class most associated with these effects …
Hodgkin Lymphoma treatment, to suggest the drug class most associated with these effects …
Multi-targeted immunotherapeutics to treat B cell malignancies
The concept of multi-targeted immunotherapeutic systems has propelled the field of cancer
immunotherapy into an exciting new era. Multi-effector molecules can be designed to …
immunotherapy into an exciting new era. Multi-effector molecules can be designed to …
[PDF][PDF] Macrophage-Based Therapeutic Strategies in Hematologic Malignancies. Cancers 2023, 15, 3722
S Khalili, F Zeinali, A Moghadam Fard, SR Taha… - 2023 - researchgate.net
Macrophages are types of immune cells, with ambivalent functions in tumor growth, which
depend on the specific environment in which they reside. Tumor-associated macrophages …
depend on the specific environment in which they reside. Tumor-associated macrophages …