Emerging findings suggest that brain-derived neurotrophic factor (BDNF) serves widespread
roles in regulating energy homeostasis by controlling patterns of feeding and physical …

Stressors ranging from psychogenic/social to neurogenic/injury to systemic/microbial can
impact microglial inflammatory processes, but less is known regarding their effects on …

Chondrosarcomas are a type of primary malignant bone cancer, with a potent capacity for
local invasion and distant metastasis. Brain-derived neurotrophic factor (BDNF) is commonly …

The circadian clock regulates rhythms in gene transcription that have a profound impact on
cellular function, behavior, and disease. Circadian dysfunction is a symptom of aging and …

Simple Summary Most organisms living at the surface of the Earth have evolved biological
clocks to cope with an environment characterized by the alternation of nights and days. For …

The measurement of circulating levels of brain-derived neurotrophic factor (BDNF) has been
proposed to be a marker of disease and an indicator of recovery. Thus, knowing the …

Diet and circadian rhythms have been found to have a profound impact on health, disease,
and aging. Skipping breakfast, eating late, and overeating have adverse effects on the …

In both vertebrate and invertebrate brains, neurons, glial cells and synapses are plastic,
which means that the physiology and structure of these components are modified in …

Genetic and environmental models of neuropsychiatric disease have grown exponentially
over the last 20 years. One measure that is often used to evaluate the translational …

The brain-derived neurotrophic factor (BDNF) activates its receptor, tropomyosin receptor
kinase B (TrkB; also called NTRK2) that has been shown to promote the malignant …