Rheumatoid arthritis (RA) is a chronic systemic autoimmune disease that primarily affects
the lining of the synovial joints and is associated with progressive disability, premature …

The development of changes on X-rays in patients with rheumatoid arthritis (RA), as
described in the literature, is presented. Prospective studies on patients with early disease …

Introduction Frequent assessments of rheumatoid arthritis (RA) disease activity allow timely
adaptation of therapy, which is essential in preventing disease progression. However …

Objective Tumor necrosis factor (TNF) is an important proinflammatory cytokine that
mediates inflammatory synovitis and articular matrix degradation in rheumatoid arthritis …

Objective. Delay of disease-modifying anti-rheumatic drug (DMARD) therapy is a major
contributing factor for poor outcome in rheumatoid arthritis (RA). Although early therapy has …

Rheumatoid arthritis (RA) is an autoimmune disorder of unknown etiology characterized by
symmetric, erosive synovitis and, in some cases, extraarticular involvement (1). Most …

Objective. To compare the benefits of initiating treatment with methotrexate (MTX) and
infliximab (anti–tumor necrosis factor [anti-TNF] monoclonal antibody) with those of MTX …

Objective To evaluate the efficacy and safety of anakinra in combination with methotrexate
(MTX) in patients with active rheumatoid arthritis (RA). Methods Patients with moderate‐to …

▪ Objective: To explore the role of HLA-DRB1 genes in determining disease severity in
rheumatoid arthritis.▪ Design: Case series of patients with seropositive rheumatoid arthritis.▪ …

Objective. To compare the clinical efficacy and safety of leflunomide and methotrexate for
the treatment of rheumatoid arthritis (RA). Methods. In this multicentre, double‐blind trial …