There is a genetic component to human obesity that accounts for 40% to 50% of the
variability in body weight status but that is lower among normal weight individuals (about …

Mendelian randomization (MR) is increasingly used to make causal inferences in a wide
range of fields, from drug development to etiologic studies. Causal inference in MR is …

Estimates from Mendelian randomization studies of unrelated individuals can be biased due
to uncontrolled confounding from familial effects. Here we describe methods for within-family …

Positive correlations between mates can increase trait variation and prevalence, as well as
bias estimates from genetically informed study designs. While past studies of similarity …

How much of our fate is tied to the status of our parents and grandparents? How much does
it influence our children? More than we wish to believe. While it has been argued that rigid …

In human populations, assortative mating is almost universally positive, with similarities
between partners for quantitative phenotypes–, common disease risk,,–, behaviour,, social …

Assortative mating on heritable traits can have implications for the genetic resemblance
between siblings and in-laws in succeeding generations. We studied polygenic scores and …

In this systematic review, we aimed to collect together all previous twin and adoption studies
on childhood and adolescent obesity up to the age of 18 years. Using several sources, we …

Hybridization has long been considered a process that prevents divergence between
species. In contrast to this historical view, an increasing number of empirical studies claim to …

Amajor component of variation in body height is due to genetic differences, but
environmental factors have a substantial contributory effect. In this study we aimed to …