Global burden of hepatitis B virus: current status, missed opportunities and a call for action

YC Hsu, DQ Huang, MH Nguyen - Nature Reviews Gastroenterology & …, 2023 - nature.com
Chronic hepatitis B virus (HBV) infection affects about 296 million people worldwide and is
the leading aetiology of cirrhosis and liver cancer globally. Major medical complications also …

Point-of-care diagnostics: recent developments in a connected age

S Nayak, NR Blumenfeld, T Laksanasopin… - Analytical …, 2017 - ACS Publications
The field of point-of-care (POC) diagnostics offers the tantalizing possibility of providing
rapid diagnostic results in nonlaboratory settings. Here, we review progress in this research …

[图书][B] WHO guidelines on hepatitis B and C testing

World Health Organization - 2017 - apps.who.int
Web Annexes Page 1 Page | i GUIDELINES ON HEPATITIS B AND C TESTING February 2017
GUIDELINES ANNEXES Page 2 Page | ii WHO guidelines on hepatitis B and C testing ISBN …

Hepatitis B in sub-Saharan Africa: strategies to achieve the 2030 elimination targets

CW Spearman, M Afihene, R Ally, B Apica… - The lancet …, 2017 - thelancet.com
The WHO global health sector strategy on viral hepatitis, created in May, 2016, aims to
achieve a 90% reduction in new cases of chronic hepatitis B and C and a 65% reduction in …

The gamma-glutamyl transpeptidase to platelet ratio (GPR) predicts significant liver fibrosis and cirrhosis in patients with chronic HBV infection in West Africa

M Lemoine, Y Shimakawa, S Nayagam, M Khalil… - Gut, 2016 - gut.bmj.com
Background Simple and inexpensive non-invasive fibrosis tests are highly needed but have
been poorly studied in sub-Saharan Africa. Methods Using liver histology as a gold …

Hepatitis B virus: advances in prevention, diagnosis, and therapy

MH Nguyen, G Wong, E Gane, JH Kao… - Clinical microbiology …, 2020 - Am Soc Microbiol
Currently, despite the use of a preventive vaccine for several decades as well as the use of
effective and well-tolerated viral suppressive medications since 1998, approximately 250 …

Global disparities in hepatitis B elimination—a focus on Africa

MW Sonderup, CW Spearman - Viruses, 2022 - mdpi.com
In 2016, WHO member states at the World Health Assembly adopted a Global Health Sector
Strategy that included a policy of eliminating viral hepatitis. Clear targets were established to …

Acceptability and feasibility of a screen-and-treat programme for hepatitis B virus infection in The Gambia: the Prevention of Liver Fibrosis and Cancer in Africa …

M Lemoine, Y Shimakawa, R Njie, M Taal… - The Lancet Global …, 2016 - thelancet.com
Background Despite the introduction of immunisation for hepatitis B virus (HBV) in the
1990s, HBV-related morbidity and mortality remain high in sub-Saharan Africa. Identification …

New and old biomarkers for diagnosis and management of chronic hepatitis B virus infection

CS Coffin, K Zhou, NA Terrault - Gastroenterology, 2019 - Elsevier
Tests to detect the presence and activity of hepatitis B virus (HBV) are the cornerstones of
diagnosis and management. Assays that detect or measure serum levels of HB surface …

A global investment framework for the elimination of hepatitis B

J Howell, A Pedrana, SE Schroeder, N Scott… - Journal of …, 2021 - Elsevier
Background & Aims More than 292 million people are living with hepatitis B worldwide and
are at risk of death from cirrhosis and liver cancer. The World Health Organization (WHO) …