Simple Summary AML is a type of leukemia with a very unfavorable prognosis. Some of the
new therapeutic targets that are being investigated by researchers worldwide are …

Simple Summary Childhood acute myeloid leukemia (AML) remains a cancer with poor
overall outcomes. Myeloid sarcomas (MS) are extramedullary masses of leukemia cells that …

Identifying mechanisms underlying relapse is a major clinical issue for effective cancer
treatment. The emerging understanding of the importance of metastasis in hematologic …

Extramedullary deposits of acute myeloid leukemia (eAML), constitute an unusual
presentation or complication of AML, which can occur in isolation (isolated eAML) or in the …

Extramedullary infiltration (EMI) is a concomitant manifestation that may indicate poor
outcome of acute myeloid leukemia (AML). The underlying mechanism remains poorly …

Extramedullary (EM) colonization is a rare complication of acute myeloid leukemia (AML),
occurring in about 10% of patients, but the processes underlying tissue invasion are not …

Myeloid sarcoma (MS) is a distinct entity among myeloid neoplasms defined as a tumour
mass of myeloid blasts occurring at an anatomical site other than the bone marrow, in most …

Backgrounds The incidence of extramedullary diseases (EMDs) in patients diagnosed with
acute myeloid leukemia (AML) is approximately 10–20%. These patients exhibit a …

Myeloid Sarcoma (MS) is a high grade, hematological malignancy defined as an
extramedullary tumor mass of myeloid blasts with or without maturation that effaces tissue …

Objectives Leukemia cutis is a conflicting term to describe neoplastic hematopoietic
infiltrates in the skin. Cutaneous myeloid or lymphoid proliferations often present a serious …