Early actions of neurotransmitters during cortex development and maturation of reprogrammed neurons

J Ojeda, A Ávila - Frontiers in Synaptic Neuroscience, 2019 - frontiersin.org
The development of the brain is shaped by a myriad of factors among which
neurotransmitters play remarkable roles before and during the formation and maturation of …

[HTML][HTML] Associations between green space and preterm birth: Windows of susceptibility and interaction with air pollution

Y Sun, P Sheridan, O Laurent, J Li, DA Sacks… - Environment …, 2020 - Elsevier
Background Recent studies have reported inconsistent associations between maternal
residential green space and preterm birth (PTB, born< 37 completed gestational weeks). In …

Mutations associated with neuropsychiatric conditions delineate functional brain connectivity dimensions contributing to autism and schizophrenia

CA Moreau, SGW Urchs, K Kuldeep, P Orban… - Nature …, 2020 - nature.com
Abstract 16p11. 2 and 22q11. 2 Copy Number Variants (CNVs) confer high risk for Autism
Spectrum Disorder (ASD), schizophrenia (SZ), and Attention-Deficit-Hyperactivity-Disorder …

Genotoxic damage during brain development presages prototypical neurodegenerative disease

GE Kisby, PS Spencer - Frontiers in Neuroscience, 2021 - frontiersin.org
Western Pacific Amyotrophic Lateral Sclerosis and Parkinsonism-Dementia Complex
(ALS/PDC) is a disappearing prototypical neurodegenerative disorder (tau-dominated …

NOCICEPTRA: gene and microRNA signatures and their trajectories characterizing human iPSC‐derived nociceptor maturation

M Zeidler, KK Kummer, CL Schöpf… - Advanced …, 2021 - Wiley Online Library
Nociceptors are primary afferent neurons serving the reception of acute pain but also the
transit into maladaptive pain disorders. Since native human nociceptors are hardly available …

Superiority of quadratic over conventional neural networks for classification of gaussian mixture data

T Qi, G Wang - Visual Computing for Industry, Biomedicine, and Art, 2022 - Springer
To enrich the diversity of artificial neurons, a type of quadratic neurons was proposed
previously, where the inner product of inputs and weights is replaced by a quadratic …

The homeobox transcription factor Cux1 coordinates postnatal epithelial developmental timing but is dispensable for lung organogenesis and regeneration

B Zhao, J Socha, A Toth, S Fernandes… - American Journal of …, 2024 - atsjournals.org
Lung epithelial progenitors use a complex network of known and predicted transcriptional
regulators to influence early lung development. Here, we evaluate the function of one …

Petagraph: A large-scale unifying knowledge graph framework for integrating biomolecular and biomedical data

BJ Stear, T Mohseni Ahooyi, JA Simmons, C Kollar… - Scientific Data, 2024 - nature.com
Over the past decade, there has been substantial growth in both the quantity and complexity
of available biomedical data. In order to more efficiently harness this extensive data and …

Encore: a visualization tool for insight into circadian omics

H De los Santos, KP Bennett, JM Hurley - Proceedings of the 10th ACM …, 2019 - dl.acm.org
Circadian rhythms are 24-hour biological cycles that control daily molecular rhythms in many
organisms. The cellular elements that fall under the regulation of the clock are often studied …

Functional annotation of cell type and condition specific schizophrenia associated non-coding genetic variants in disease relevant cell types

CK Rummel - 2023 - edoc.ub.uni-muenchen.de
Psychiatric diseases are a major public health burden worldwide, yet little is known about
their underlying molecular mechanisms. Among those highly polygenic diseases …