Early actions of neurotransmitters during cortex development and maturation of reprogrammed neurons
The development of the brain is shaped by a myriad of factors among which
neurotransmitters play remarkable roles before and during the formation and maturation of …
neurotransmitters play remarkable roles before and during the formation and maturation of …
[HTML][HTML] Associations between green space and preterm birth: Windows of susceptibility and interaction with air pollution
Y Sun, P Sheridan, O Laurent, J Li, DA Sacks… - Environment …, 2020 - Elsevier
Background Recent studies have reported inconsistent associations between maternal
residential green space and preterm birth (PTB, born< 37 completed gestational weeks). In …
residential green space and preterm birth (PTB, born< 37 completed gestational weeks). In …
Mutations associated with neuropsychiatric conditions delineate functional brain connectivity dimensions contributing to autism and schizophrenia
Abstract 16p11. 2 and 22q11. 2 Copy Number Variants (CNVs) confer high risk for Autism
Spectrum Disorder (ASD), schizophrenia (SZ), and Attention-Deficit-Hyperactivity-Disorder …
Spectrum Disorder (ASD), schizophrenia (SZ), and Attention-Deficit-Hyperactivity-Disorder …
Genotoxic damage during brain development presages prototypical neurodegenerative disease
GE Kisby, PS Spencer - Frontiers in Neuroscience, 2021 - frontiersin.org
Western Pacific Amyotrophic Lateral Sclerosis and Parkinsonism-Dementia Complex
(ALS/PDC) is a disappearing prototypical neurodegenerative disorder (tau-dominated …
(ALS/PDC) is a disappearing prototypical neurodegenerative disorder (tau-dominated …
NOCICEPTRA: gene and microRNA signatures and their trajectories characterizing human iPSC‐derived nociceptor maturation
Nociceptors are primary afferent neurons serving the reception of acute pain but also the
transit into maladaptive pain disorders. Since native human nociceptors are hardly available …
transit into maladaptive pain disorders. Since native human nociceptors are hardly available …
Superiority of quadratic over conventional neural networks for classification of gaussian mixture data
To enrich the diversity of artificial neurons, a type of quadratic neurons was proposed
previously, where the inner product of inputs and weights is replaced by a quadratic …
previously, where the inner product of inputs and weights is replaced by a quadratic …
The homeobox transcription factor Cux1 coordinates postnatal epithelial developmental timing but is dispensable for lung organogenesis and regeneration
B Zhao, J Socha, A Toth, S Fernandes… - American Journal of …, 2024 - atsjournals.org
Lung epithelial progenitors use a complex network of known and predicted transcriptional
regulators to influence early lung development. Here, we evaluate the function of one …
regulators to influence early lung development. Here, we evaluate the function of one …
Petagraph: A large-scale unifying knowledge graph framework for integrating biomolecular and biomedical data
BJ Stear, T Mohseni Ahooyi, JA Simmons, C Kollar… - Scientific Data, 2024 - nature.com
Over the past decade, there has been substantial growth in both the quantity and complexity
of available biomedical data. In order to more efficiently harness this extensive data and …
of available biomedical data. In order to more efficiently harness this extensive data and …
Encore: a visualization tool for insight into circadian omics
H De los Santos, KP Bennett, JM Hurley - Proceedings of the 10th ACM …, 2019 - dl.acm.org
Circadian rhythms are 24-hour biological cycles that control daily molecular rhythms in many
organisms. The cellular elements that fall under the regulation of the clock are often studied …
organisms. The cellular elements that fall under the regulation of the clock are often studied …
Functional annotation of cell type and condition specific schizophrenia associated non-coding genetic variants in disease relevant cell types
CK Rummel - 2023 - edoc.ub.uni-muenchen.de
Psychiatric diseases are a major public health burden worldwide, yet little is known about
their underlying molecular mechanisms. Among those highly polygenic diseases …
their underlying molecular mechanisms. Among those highly polygenic diseases …