Cardiac glycosides (CGs) have a long history of treating cardiac diseases. However, recent
reports have suggested that CGs also possess anticancer and antiviral activities. The …

The human cytomegalovirus (HCMV), one of eight human herpesviruses, establishes
lifelong latent infections in most people worldwide. Primary or reactivated HCMV infections …

Simple Summary Cellular senescence is considered a stress response that protects cells
against malignant transformation, facilitates tissue repair and development, and prevents …

Cardiotonic steroids (CTS) were first documented by ancient Egyptians more than 3000
years ago. Cardiotonic steroids are a group of steroid hormones that circulate in the blood of …

Since being first described more than 60 years ago, Na, K-ATPase has been extensively
studied, while novel concepts about its structure, physiology, and biological roles continue to …

Cardiotonic steroids (CTS) are a group of compounds existing in animals and plants. CTS
are commonly referred to cardiac glycosides (CGs) which are composed of sugar residues …

Glycosides represent a large group of secondary metabolic products derived from plants,
demonstrating several known functions, including growth regulation, allelopathy (inhibition …

Cardiac glycosides (CGs) are used primarily for cardiac failure and have been reported to
have other effects, including inhibition of viral replication. Here we set out to study …

Host-directed therapeutics for human cytomegalovirus (HCMV) requires elucidation of
cellular mechanisms that inhibit HCMV. We report a novel pathway used by cardiac …

Over the past 15 years, investigators have reported on the utility and safety of cardiac
glycosides for numerous health benefits including those as treatments for malignant …