In addition to the canonical right-handed double helix, other DNA structures, termed 'non-B
DNA', can form in the genomes across the tree of life. Non-B DNA regulates multiple cellular …

A complete understanding of DNA double-helical structure discovered by James Watson
and Francis Crick in 1953, unveil the importance and significance of DNA. For the last seven …

DNA is a strikingly flexible molecule and can form a variety of secondary structures,
including the triple helix, which is the subject of this review. The DNA triplex may be formed …

Fluorescence labeling and probing are fundamental techniques for nucleic acid analysis
and quantification. However, new fluorescent probes and approaches are urgently needed …

Stretches of cytosine-rich DNA are capable of adopting a dynamic secondary structure, the i-
motif. When within promoter regions, the i-motif has the potential to act as a molecular switch …

The most stable structure of DNA is the canonical right-handed double helix termed B DNA.
However, certain environments and sequence motifs favor alternative conformations, termed …

Artificial receptors for hydrophobic molecules usually have moderate affinities and limited
selectivities. We describe three new classes of high affinity hydrophobic receptors for …

Alternative DNA structures that differ from the canonical B-form of DNA can arise from
repetitive sequences and play beneficial roles in many cellular processes such as gene …

DNA hydrogels are self-assembled biomaterials that rely on Watson–Crick base pairing to
form large-scale programmable three-dimensional networks of nanostructured DNA …

Over the past decade, appreciation of the roles of G-quadruplex (G4) structures in cellular
regulation and maintenance has rapidly grown, making the establishment of robust methods …