Poly (A) tail elongation after export of an messenger RNA (mRNA) to the cytoplasm is called
cytoplasmic polyadenylation. It was first discovered in oocytes and embryos, where it has …

Mucins are high molecular weight glycoproteins that play important roles in diagnostic and
prognostic prediction and in carcinogenesis and tumor invasion. Regulation of expression of …

Putative RNA-binding proteins (RBPs), zygote arrested-1 (ZAR1), and ZAR2 (also known as
ZAR1L), have been identified as maternal factors that mainly function in oogenesis and …

Oogenesis is a complex process regulated by precise coordination of multiple factors,
including maternal genes. Zygote arrest 1 (zar1) has been identified as an ovary-specific …

Background Cancer still is one of the leading causes of death and its death toll is predicted
to rise further. We identified earlier the potential tumour suppressor zygote arrest 1 (ZAR1) to …

The key transcription factors of T helper cell subpopulations, including T-bet, GATA3, RORγt,
and Foxp3 are involved in various autoimmune diseases. Whether methylation of these …

Context: Aberrant hypermethylation of promoter region of tumor suppressor genes could be
used as cancer biomarkers. Objective: To test methylation status of ZAR1 and SFRP4 …

Zygote arrest (Zar) proteins are crucial for early embryonic development, but their molecular
mechanism of action is unknown. The Translational Control Sequence (TCS) in the 3 …

Background Lung cancer is the leading cause of cancer-related deaths with 1.8 million new
cases each year and poor 5-year prognosis. Promoter hypermethylation of tumour …

Aberrant methylation change of IRF8 confers risk to various tumors, and abnormal
expression of IRF8 is involved in many autoimmune diseases, including ocular Behcet's …