Prospects and challenges of extracellular vesicle-based drug delivery system: considering cell source
W Meng, C He, Y Hao, L Wang, L Li, G Zhu - Drug delivery, 2020 - Taylor & Francis
Extracellular vesicles (EVs), including exosomes, microvesicles, and apoptotic bodies, are
nanosized membrane vesicles derived from most cell types. Carrying diverse biomolecules …
nanosized membrane vesicles derived from most cell types. Carrying diverse biomolecules …
Drug delivery with extracellular vesicles: from imagination to innovation
OG De Jong, SAA Kooijmans, DE Murphy… - Accounts of chemical …, 2019 - ACS Publications
Conspectus Extracellular vesicles are nanoparticles produced by cells. They are composed
of cellular membrane with associated membrane proteins that surrounds an aqueous core …
of cellular membrane with associated membrane proteins that surrounds an aqueous core …
Paclitaxel is incorporated by mesenchymal stromal cells and released in exosomes that inhibit in vitro tumor growth: a new approach for drug delivery
L Pascucci, V Coccè, A Bonomi, D Ami… - Journal of controlled …, 2014 - Elsevier
Mesenchymal stromal cells (MSCs) have been proposed for delivering anticancer agents
because of their ability to home in on tumor microenvironment. We found that MSCs can …
because of their ability to home in on tumor microenvironment. We found that MSCs can …
Concise review: mesenchymal stem cell-based drug delivery: the good, the bad, the ugly, and the promise
TEG Krueger, DLJ Thorek… - Stem cells …, 2018 - academic.oup.com
The development of mesenchymal stem cells (MSCs) as cell-based drug delivery vectors for
numerous clinical indications, including cancer, has significant promise. However, a …
numerous clinical indications, including cancer, has significant promise. However, a …
[HTML][HTML] A new approach for loading anticancer drugs into mesenchymal stem cell-derived exosome mimetics for cancer therapy
Exosomes derived from mesenchymal stem cells (MSCs) have been evaluated for their
potential to be used as drug delivery vehicles. Synthetically personalized exosome mimetics …
potential to be used as drug delivery vehicles. Synthetically personalized exosome mimetics …
[HTML][HTML] Small extracellular vesicles in cancer
Extracellular vesicles (EV) are lipid-bilayer enclosed vesicles in submicron size that are
released from cells. A variety of molecules, including proteins, DNA fragments, RNAs, lipids …
released from cells. A variety of molecules, including proteins, DNA fragments, RNAs, lipids …
Mesenchymal stromal cells in cancer: a review of their immunomodulatory functions and dual effects on tumor progression
S Galland, I Stamenkovic - The Journal of pathology, 2020 - Wiley Online Library
Mesenchymal stem or stromal cells (MSCs) are pluripotent cells implicated in a broad range
of physiological events, including organogenesis and maintenance of tissue homeostasis as …
of physiological events, including organogenesis and maintenance of tissue homeostasis as …
[HTML][HTML] The extracellular matrix in pancreatic cancer: description of a complex network and promising therapeutic options
Simple Summary This review depicts the principal mechanisms involved in the process of
stromal desmoplasia characterizing pancreatic ductal adenocarcinoma (PDAC). The aim of …
stromal desmoplasia characterizing pancreatic ductal adenocarcinoma (PDAC). The aim of …
[HTML][HTML] Mesenchymal stem cells as a cornerstone in a galaxy of intercellular signals: basis for a new era of medicine
S Fernández-Francos, N Eiro, LA Costa… - International journal of …, 2021 - mdpi.com
Around 40% of the population will suffer at some point in their life a disease involving tissue
loss or an inflammatory or autoimmune process that cannot be satisfactorily controlled with …
loss or an inflammatory or autoimmune process that cannot be satisfactorily controlled with …
[HTML][HTML] Engineering extracellular vesicles as nanotherapeutics for regenerative medicine
L Ramasubramanian, P Kumar, A Wang - Biomolecules, 2019 - mdpi.com
Long thought of to be vesicles that primarily recycled waste biomolecules from cells,
extracellular vesicles (EVs) have now emerged as a new class of nanotherapeutics for …
extracellular vesicles (EVs) have now emerged as a new class of nanotherapeutics for …