Systems Medicine as a Strategy to Deal with Alzheimer's Disease

XX Zeng, JB Zeng - Journal of Alzheimer's Disease, 2023 - content.iospress.com
The traits of Alzheimer's disease (AD) include amyloid plaques made of Aβ 1-40 and Aβ 1-
42, and neurofibrillary tangles by the hyperphosphorylation of tau protein. AD is a complex …

Inositol trisphosphate and ryanodine receptor signaling distinctly regulate neurite pathfinding in response to engineered micropatterned surfaces

JT Vecchi, M Rhomberg, C Allan Guymon, MR Hansen - PloS one, 2024 - journals.plos.org
Micro and nanoscale patterning of surface features and biochemical cues have emerged as
tools to precisely direct neurite growth into close proximity with next generation neural …