Development of human respiratory airway models: A review

K Ahookhosh, O Pourmehran, H Aminfar… - European Journal of …, 2020 - Elsevier
Pulmonary drug delivery has gained great interest as an important subject of research over
the past decades given the lung diseases which are affecting millions of people suffer from …

Modeling airflow and particle transport/deposition in pulmonary airways

C Kleinstreuer, Z Zhang, Z Li - Respiratory physiology & neurobiology, 2008 - Elsevier
A review of research papers is presented, pertinent to computer modeling of airflow as well
as nano-and micron-size particle deposition in pulmonary airway replicas. The key modeling …

Validation of computational fluid dynamics in CT-based airway models with SPECT/CT

JW De Backer, WG Vos, SC Vinchurkar, R Claes… - Radiology, 2010 - pubs.rsna.org
Purpose To compare the results obtained by using numerical flow simulations with the
results of combined single photon emission computed tomography (SPECT) and computed …

A coupled cell-based smoothed finite element method and discrete phase model for incompressible laminar flow with dilute solid particles

T Wang, G Zhou, C Jiang, F Shi, X Tian… - Engineering Analysis with …, 2022 - Elsevier
In this paper, the cell-based smoothed finite element method (CS-FEM) empowered by the
discrete phase model (DPM) is developed to solve dilute solid particles movements induced …

Modeling the bifurcating flow in a CT-scanned human lung airway

HY Luo, Y Liu - Journal of Biomechanics, 2008 - Elsevier
The inspiratory flow characteristics in a CT-scanned human lung model were numerically
investigated using low Reynolds number (LRN) κ–ω turbulent model. The five-generation …

An overview of experiments and numerical simulations on airflow and aerosols deposition in human airways and the role of bioaerosol motion in COVID-19 …

JK Mutuku, WC Hou, WH Chen - Aerosol and Air Quality Research, 2020 - aaqr.org
Determining the hotspots and deposition efficiencies (DEs) for aerosols in human airways is
important for both research and medical purposes. The complexity of the human airways …

[HTML][HTML] A computational study of the respiratory airflow characteristics in normal and obstructed human airways

B Sul, A Wallqvist, MJ Morris, J Reifman… - Computers in biology and …, 2014 - Elsevier
Obstructive lung diseases in the lower airways are a leading health concern worldwide. To
improve our understanding of the pathophysiology of lower airways, we studied airflow …

Numerical investigation of particle deposition in a triple bifurcation airway due to gravitational sedimentation and inertial impaction

X Chen, Y Feng, W Zhong, B Sun, F Tao - Powder Technology, 2018 - Elsevier
Focusing on the particle deposition due to gravitational sedimentation and inertial impaction,
the transport and deposition of micron particles with various diameters (ie, 1 to 7 μm) have …

Magnetic aerosol drug targeting in lung cancer therapy using permanent magnet

MKD Manshadi, M Saadat, M Mohammadi… - Drug …, 2019 - Taylor & Francis
Primary bronchial cancer accounts for almost 20% of all cancer death worldwide. One of the
emerging techniques with tremendous power for lung cancer therapy is magnetic aerosol …

Structural and functional alterations of the tracheobronchial tree after left upper pulmonary lobectomy for lung cancer

Q Gu, S Qi, Y Yue, J Shen, B Zhang, W Sun… - Biomedical engineering …, 2019 - Springer
Background Pulmonary lobectomy has been a well-established curative treatment method
for localized lung cancer. After left upper pulmonary lobectomy, the upward displacement of …