Validity and utility of Hierarchical Taxonomy of Psychopathology (HiTOP): III. Emotional dysfunction superspectrum
The Hierarchical Taxonomy of Psychopathology (HiTOP) is a quantitative nosological
system that addresses shortcomings of traditional mental disorder diagnoses, including …
system that addresses shortcomings of traditional mental disorder diagnoses, including …
Sources of individual differences in pain
JS Mogil - Annual Review of Neuroscience, 2021 - annualreviews.org
Pain is an immense clinical and societal challenge, and the key to understanding and
treating it is variability. Robust interindividual differences are consistently observed in pain …
treating it is variability. Robust interindividual differences are consistently observed in pain …
The genetic basis of endometriosis and comorbidity with other pain and inflammatory conditions
Endometriosis is a common condition associated with debilitating pelvic pain and infertility.
A genome-wide association study meta-analysis, including 60,674 cases and 701,926 …
A genome-wide association study meta-analysis, including 60,674 cases and 701,926 …
Multi-ancestry genome-wide association study of cannabis use disorder yields insight into disease biology and public health implications
As recreational use of cannabis is being decriminalized in many places and medical use
widely sanctioned, there are growing concerns about increases in cannabis use disorder …
widely sanctioned, there are growing concerns about increases in cannabis use disorder …
[HTML][HTML] A cellular taxonomy of the adult human spinal cord
The mammalian spinal cord functions as a community of cell types for sensory processing,
autonomic control, and movement. While animal models have advanced our understanding …
autonomic control, and movement. While animal models have advanced our understanding …
Single cell transcriptomics of primate sensory neurons identifies cell types associated with chronic pain
Distinct types of dorsal root ganglion sensory neurons may have unique contributions to
chronic pain. Identification of primate sensory neuron types is critical for understanding the …
chronic pain. Identification of primate sensory neuron types is critical for understanding the …
GWAS meta-analysis of suicide attempt: identification of 12 genome-wide significant loci and implication of genetic risks for specific health factors
AR Docherty, N Mullins… - American journal of …, 2023 - Am Psychiatric Assoc
Objective: Suicidal behavior is heritable and is a major cause of death worldwide. Two large-
scale genome-wide association studies (GWASs) recently discovered and cross-validated …
scale genome-wide association studies (GWASs) recently discovered and cross-validated …
Elevated dementia risk, cognitive decline, and hippocampal atrophy in multisite chronic pain
Numerous studies have investigated the impacts of common types of chronic pain (CP) on
patients' cognitive function and observed that CP was associated with later dementia. More …
patients' cognitive function and observed that CP was associated with later dementia. More …
[HTML][HTML] Predicting chronic postsurgical pain: current evidence and a novel program to develop predictive biomarker signatures
Chronic pain affects more than 50 million Americans. Treatments remain inadequate, in
large part, because the pathophysiological mechanisms underlying the development of …
large part, because the pathophysiological mechanisms underlying the development of …
Genetic risk factors have a substantial impact on healthy life years
The impact of genetic variation on overall disease burden has not been comprehensively
evaluated. We introduce an approach to estimate the effect of genetic risk factors on …
evaluated. We introduce an approach to estimate the effect of genetic risk factors on …