Targeting Akt/CREB/BDNF signaling pathway by ginsenosides in neurodegenerative diseases: A mechanistic approach

SN Zarneshan, S Fakhri, H Khan - Pharmacological research, 2022 - Elsevier
Neurodegenerative diseases (NDDs) are leading causes of death and morbidity in the
elderly worldwide. From the mechanistic/pathological view, oxidative stress, inflammation …

[HTML][HTML] Ginsenoside compound K: Insights into recent studies on pharmacokinetics and health-promoting activities

A Sharma, HJ Lee - Biomolecules, 2020 - mdpi.com
Ginseng (Panax ginseng) is an herb popular for its medicinal and health properties.
Compound K (CK) is a secondary ginsenoside biotransformed from major ginsenosides …

[HTML][HTML] Ginsenosides emerging as both bifunctional drugs and nanocarriers for enhanced antitumor therapies

H Wang, Y Zheng, Q Sun, Z Zhang, M Zhao… - Journal of …, 2021 - Springer
Ginsenosides, the main components isolated from Panax ginseng, can play a therapeutic
role by inducing tumor cell apoptosis and reducing proliferation, invasion, metastasis; by …

Applications and advancements of nanoparticle-based drug delivery in alleviating lung cancer and chronic obstructive pulmonary disease

G De Rubis, KR Paudel, L Corrie, S Mehndiratta… - Naunyn-Schmiedeberg's …, 2024 - Springer
Lung cancer (LC) and chronic obstructive pulmonary disease (COPD) are among the
leading causes of mortality worldwide. Cigarette smoking is among the main aetiologic …

Perspectives and controversies regarding the use of natural products for the treatment of lung cancer

T Wen, L Song, S Hua - Cancer Medicine, 2021 - Wiley Online Library
Lung cancer is the leading cause of cancer‐related mortality both in men and women and
accounts for 18.4% of all cancer‐related deaths. Although advanced therapy methods have …

Anticancer activities of ginsenosides, the main active components of ginseng

H Hong, D Baatar, SG Hwang - … ‐Based Complementary and …, 2021 - Wiley Online Library
Cancer incidence rate has been increasing drastically in recent years. One of the many
cancer treatment methods is chemotherapy. Traditional medicine, in the form of …

[HTML][HTML] Production of minor ginsenoside CK from major ginsenosides by biotransformation and its advances in targeted delivery to tumor tissues using …

M Murugesan, R Mathiyalagan, V Boopathi, BM Kong… - Nanomaterials, 2022 - mdpi.com
For over 2000 years, ginseng (roots of Panax ginseng CA Meyer) has been used as a
traditional herbal medicine. Ginsenosides are bioactive compounds present in ginseng …

Protein and peptide delivery to lungs by using advanced targeted drug delivery

DK Chellappan, P Prasher, V Saravanan… - Chemico-biological …, 2022 - Elsevier
The challenges and difficulties associated with conventional drug delivery systems have led
to the emergence of novel, advanced targeted drug delivery systems. Therapeutic drug …

Ginsenosides: a potential natural medicine to protect the lungs from lung cancer and inflammatory lung disease

L Wang, Y Zhang, Z Song, Q Liu, D Fan, X Song - Food & Function, 2023 - pubs.rsc.org
Lung cancer is the malignancy with the highest morbidity and mortality. Additionally,
pulmonary inflammatory diseases, such as pneumonia, acute lung injury, chronic obstructive …

Anticancer properties and pharmaceutical applications of ginsenoside compound K: A review

L Zhou, ZK Li, CY Li, YQ Liang… - Chemical biology & drug …, 2022 - Wiley Online Library
Ginsenoside compound K (CK) is the major intestinal bacterial metabolite of ginsenosides
that exhibits anticancer potential in various cancer cells both in vitro and in vivo. The …