Gut microbiome-mediated mechanisms for reducing cholesterol levels: implications for ameliorating cardiovascular disease

B Jia, Y Zou, X Han, JW Bae, CO Jeon - Trends in Microbiology, 2023 - cell.com
Cardiovascular disease (CVD) is a health problem worldwide, and elevated cholesterol
levels are a key risk factor for the disease. Dysbiotic gut microbiota has been shown to be …

The mutual interplay of gut microbiota, diet and human disease

P Illiano, R Brambilla, C Parolini - The FEBS journal, 2020 - Wiley Online Library
The intestinal milieu harbours the gut microbiota, consisting of a complex community of
bacteria, archaea, fungi, viruses and protozoans that bring to the host organism an …

Interactions between gut bacteria and bile in health and disease

SL Long, CGM Gahan, SA Joyce - Molecular aspects of medicine, 2017 - Elsevier
Bile acids are synthesized from cholesterol in the liver and released into the intestine to aid
the digestion of dietary lipids. The host enzymes that contribute to bile acid synthesis in the …

Microbial medicine: prebiotic and probiotic functional foods to target obesity and metabolic syndrome

M Green, K Arora, S Prakash - International journal of molecular sciences, 2020 - mdpi.com
Obesity has become a global epidemic and a public health crisis in the Western World,
experiencing a threefold increase in prevalence since 1975. High-caloric diets and …

Role of gut microbiota and their metabolites on atherosclerosis, hypertension and human blood platelet function: a review

AK Duttaroy - Nutrients, 2021 - mdpi.com
Emerging data have demonstrated a strong association between the gut microbiota and the
development of cardiovascular disease (CVD) risk factors such as atherosclerosis …

Bile acid receptors FXR and TGR5 signaling in fatty liver diseases and therapy

JYL Chiang, JM Ferrell - American Journal of Physiology …, 2020 - journals.physiology.org
Bile acid synthesis is the most significant pathway for catabolism of cholesterol and for
maintenance of whole body cholesterol homeostasis. Bile acids are physiological …

Gut microbiota as a potential target of metabolic syndrome: the role of probiotics and prebiotics

M He, B Shi - Cell & bioscience, 2017 - Springer
Metabolic syndrome (MS) comprises central obesity, increased plasma glucose levels,
hyperlipidemia and hypertension, and its incidence is increasing due to changes in lifestyle …

Lactic acid bacteria and bifidobacteria with potential to design natural biofunctional health-promoting dairy foods

DM Linares, C Gómez, E Renes, JM Fresno… - Frontiers in …, 2017 - frontiersin.org
Consumer interest in healthy lifestyle and health-promoting natural products is a major
driving force for the increasing global demand of biofunctional dairy foods. A number of …

Polyphenol effects on cholesterol metabolism via bile acid biosynthesis, CYP7A1: a review

KF Chambers, PE Day, HT Aboufarrag, PA Kroon - Nutrients, 2019 - mdpi.com
Atherosclerosis, the main contributor to coronary heart disease, is characterised by an
accumulation of lipids such as cholesterol in the arterial wall. Reverse cholesterol transport …

Guts and gall: bile acids in regulation of intestinal epithelial function in health and disease

P Hegyi, J Maléth, JR Walters… - Physiological …, 2018 - journals.physiology.org
Epithelial cells line the entire surface of the gastrointestinal tract and its accessory organs
where they primarily function in transporting digestive enzymes, nutrients, electrolytes, and …