Cisplatin is one of the most widely used and most potent chemotherapy drugs. However,
side effects in normal tissues and organs, notably nephrotoxicity in the kidneys, limit the use …

cis-Diamminedichloroplatinum (II)(cisplatin) is an important chemotherapeutic agent useful
in the treatment of several cancers; however, it has several side effects such as …

Cisplatin is among the most effective chemotherapeutic agents against solid tumors.
Nephrotoxicity is the most common side effect of cisplatin chemotherapy, which limits the …

Nephrotoxicity is an important complication in cancer patients undergoing cisplatin therapy.
Oxidative stress, inflammation and apoptosis/necrosis are the major patho-mechanisms of …

Cisplatin (cis-diamminedichloroplatinum (II)) is an effective agent against various solid
tumours. Despite its effectiveness, the dose of cisplatin that can be administered is limited by …

Cisplatin is an effective anti-cancer drug; however, its clinical use is usually associated with
nephrotoxicity as a dose-limiting side effect. Several molecular mechanisms have been …

The aim of this study was to investigate the possible protective role of antioxidant treatment
with ellagic acid on cisplatin‐induced nephrotoxicity using biochemical and histopatological …

Nephrotoxicity is one of the serious dose limiting side effects of cisplatin when used in the
treatment of various malignant conditions. Accumulating evidence suggests that oxidative …

Cisplatin is chemotherapeutic drug used in treatment of malignancies. However, its clinical
utility is limited by nephrotoxicity. The purpose of present study is to investigate biochemical …

Introduction: Cisplatin is an effective chemotherapeutic agent commonly used in the
treatment of malignant tumours, but ototoxicity is a significant side effect. Objectives: To …