[HTML][HTML] Crosstalk between oxidative stress and inflammatory liver injury in the pathogenesis of alcoholic liver disease
Alcoholic liver disease (ALD) is characterized by the injury, inflammation, and scarring in the
liver owing to excessive alcohol consumption. Currently, ALD is a leading cause for liver …
liver owing to excessive alcohol consumption. Currently, ALD is a leading cause for liver …
[HTML][HTML] Transcriptional and epigenetic regulation of monocyte and macrophage dysfunction by chronic alcohol consumption
DC Malherbe, I Messaoudi - Frontiers in immunology, 2022 - frontiersin.org
Drinking alcohol, even in moderation, can affect the immune system. Studies have shown
disproportionate effects of alcohol on circulating and tissue-resident myeloid cells …
disproportionate effects of alcohol on circulating and tissue-resident myeloid cells …
[HTML][HTML] Recent advances in understanding of pathogenesis of alcohol-associated liver disease
Alcohol-associated liver disease (ALD) is one of the major diseases arising from chronic
alcohol consumption and is one of the most common causes of liver-related morbidity and …
alcohol consumption and is one of the most common causes of liver-related morbidity and …
[HTML][HTML] Macrophage‐derived MLKL in alcohol‐associated liver disease: Regulation of phagocytosis
Abbreviations: ABCA1, ATP binding cassette subfamily A member; AH, alcohol‐associated
hepatitis; ALD, alcohol‐associated liver disease; BMDM, bone marrow–derived …
hepatitis; ALD, alcohol‐associated liver disease; BMDM, bone marrow–derived …
A critical review of recent knowledge of alcohol's effects on the immunological response in different tissues
K Crotty, P Anton, LG Coleman… - Alcohol: Clinical and …, 2023 - Wiley Online Library
Alcohol misuse contributes to the dysregulation of immune responses and multiorgan
dysfunction across various tissues, which are associated with higher risk of morbidity and …
dysfunction across various tissues, which are associated with higher risk of morbidity and …
Gene deconvolution reveals aberrant liver regeneration and immune cell infiltration in alcohol‐associated hepatitis
A Kim, X Wu, DS Allende, LE Nagy - Hepatology, 2021 - Wiley Online Library
Background and Aims Acute liver damage causes hepatocyte stress and death, but in
chronic liver disease impaired hepatocyte regeneration and immune cell infiltration prevents …
chronic liver disease impaired hepatocyte regeneration and immune cell infiltration prevents …
[HTML][HTML] Hepatic toxicity of fluorene-9-bisphenol (BHPF) on CD-1 mice
L Yang, X Guo, X Mao, X Jia, Y Zhou, Y Hu… - Ecotoxicology and …, 2021 - Elsevier
Abstract Fluorene-9-bisphenol (BHPF), a substitute for bisphenol A (BPA), has been widely
used in the synthesis of polyester polymers. Studies have reported multiple BHPF toxicities …
used in the synthesis of polyester polymers. Studies have reported multiple BHPF toxicities …
[HTML][HTML] Mincle-GSDMD-mediated release of IL-1β small extracellular vesicles from hepatic macrophages in ethanol-induced liver injury
Q Zhang, W Liu, K Bulek, H Wang… - Hepatology …, 2023 - journals.lww.com
Background: Macrophage-inducible C-type lectin (Mincle) is expressed on hepatic
macrophages and senses ethanol (EtOH)-induced danger signals released from dying …
macrophages and senses ethanol (EtOH)-induced danger signals released from dying …
Gut-liver Axis: Recent concepts in pathophysiology in alcohol-associated liver disease
FR Tonetti, A Eguileor, M Mrdjen, V Pathak… - Hepatology, 2024 - journals.lww.com
The growing recognition of the role of the gut microbiome's impact on alcohol-related
diseases, especially in alcohol-associated liver disease, emphasizes the need to …
diseases, especially in alcohol-associated liver disease, emphasizes the need to …
[HTML][HTML] Single-cell transcriptomics of peripheral blood mononuclear cells indicates impaired immune and inflammatory responses in alcohol-associated hepatitis
X Liu, ZX Liu, TR Morgan, TM Norden-Krichmar - Human Immunology, 2024 - Elsevier
Alcohol-associated hepatitis (AH) is often diagnosed at advanced stages, and severe AH
usually carries poor prognosis and high short-term mortality. In addition, it is challenging to …
usually carries poor prognosis and high short-term mortality. In addition, it is challenging to …