[HTML][HTML] Immune dysfunctions and immune-based therapeutic interventions in chronic lymphocytic leukemia

V Griggio, F Perutelli, C Salvetti, E Boccellato… - Frontiers in …, 2020 - frontiersin.org
Chronic lymphocytic leukemia (CLL) is a B-cell malignancy characterized by a wide range of
tumor-induced alterations, which affect both the innate and adaptive arms of the immune …

A review of the infection pathogenesis and prophylaxis recommendations in patients with chronic lymphocytic leukemia

T Tadmor, M Welslau, I Hus - Expert Review of Hematology, 2018 - Taylor & Francis
Introduction: The majority of patients with CLL will suffer from infections during their disease,
accounting for approximately 60% of deaths in CLL. Patients are predisposed to infection …

Analysis of the risk of infection in patients with chronic lymphocytic leukemia in the era of novel therapies

ALM Williams, AM Baran, PJ Meacham… - Leukemia & …, 2018 - Taylor & Francis
We studied the risk of infections in patients with chronic lymphocytic leukemia/small
lymphocytic lymphoma (CLL). Major infections were defined as requiring hospital admission …

Chronic lymphocytic leukemia: diagnosis and treatment

P Strati, N Jain, S O'Brien - Mayo Clinic Proceedings, 2018 - Elsevier
The complexity of the treatment of patients with chronic lymphocytic leukemia has increased
substantially over the past several years as a consequence of the advent of novel biological …

Vaccination in immunocompromised host: recommendations of Italian primary immunodeficiency network centers (IPINET)

B Martire, C Azzari, R Badolato, C Canessa, E Cirillo… - Vaccine, 2018 - Elsevier
Infectious complications are a major cause of morbidity and mortality in patients with primary
or secondary immunodeficiency. Prevention of infectious diseases by vaccines is among the …

Review of indications for immunoglobulin (IG) use: narrowing the gap between supply and demand

A Brand, V De Angelis, T Vuk, O Garraud… - Transfusion clinique et …, 2021 - Elsevier
Cellular blood components and plasma-derived medicinal products (PDMPs) are obtained
from blood donated by volunteers. In a growing number of countries, in line with World …

Impact of immune parameters and immune dysfunctions on the prognosis of patients with chronic lymphocytic leukemia

C Vitale, E Boccellato, L Comba, R Jones, F Perutelli… - Cancers, 2021 - mdpi.com
Simple Summary In chronic lymphocytic leukemia (CLL), immune alterations—affecting both
the innate and adaptive immunity—are very common. As a clinical consequence, patients …

The evolving landscape of COVID‐19 and post‐COVID condition in patients with chronic lymphocytic leukemia: A study by ERIC, the European research initiative on …

A Visentin, T Chatzikonstantinou… - American journal of …, 2023 - Wiley Online Library
In this retrospective international multicenter study, we describe the clinical characteristics
and outcomes of patients with chronic lymphocytic leukemia (CLL) and related disorders …

[HTML][HTML] Management of secondary immunodeficiency in hematological malignancies in the era of modern oncology

N Shah, SS Mustafa, DC Vinh - Critical Reviews in Oncology/Hematology, 2023 - Elsevier
Secondary immunodeficiency (SID) in patients with B-cell hematological malignancies is a
common condition that presents with recurrent infection. SID is due to both the inherent …

IgA levels at diagnosis predict for infections, time to treatment, and survival in chronic lymphocytic leukemia

G Ishdorj, E Streu, P Lambert, HS Dhaliwal… - Blood …, 2019 - ashpublications.org
To better understand the relationship between baseline immunoglobulin measurements and
subsequent clinical outcomes in chronic lymphocytic leukemia (CLL), we performed a …