Cucurbitacins: a systematic review of the phytochemistry and anticancer activity

Y Cai, X Fang, C He, P Li, F Xiao, Y Wang… - The American journal of …, 2015 - World Scientific
Cucurbitacins are highly oxidized tetracyclic triterpenoids that are widely present in
traditional Chinese medicines (Cucurbitaceae family), possess strong anticancer activity …

Recent Advances in the Application of Cucurbitacins as Anticancer Agents

B Zieniuk, M Pawełkowicz - Metabolites, 2023 - mdpi.com
Cucurbitacins are tetracyclic triterpenoid secondary metabolites, widely distributed in the
Cucurbitaceae family. These bitter-tasting compounds act primarily as defense mechanisms …

Triterpenoids

RA Hill, JD Connolly - Natural product reports, 2012 - pubs.rsc.org
Covering: 2010. Previous review: Nat. Prod. Rep., 2011, 28, 1087–1117 This review covers
the isolation and structure determination of triterpenoids, including squalene derivatives …

Bryonia dioica aqueous extract induces apoptosis through mitochondrial intrinsic pathway in BL41 Burkitt's lymphoma cells

B Benarba, B Meddah, A Aoues - Journal of ethnopharmacology, 2012 - Elsevier
ETHNOPHARMACOLOGICAL RELEVANCE: Bryonia dioica Jacq. is a climbing perennial
herb with tuberous roots which is widely used in traditional medicine in Algeria for the …

The Genus Bryonia L. (Cucurbitaceae): A Systematic Review of Its Botany, Phytochemistry, Traditional Uses, and Biological Activities

B Benarba, K Belhouala - Sci, 2024 - mdpi.com
The Bryonia genus (Cucurbitaceae) is divided into 13 plants considered medicinal species
with a significant pharmacological value fortreating as well as preventing various ailments …

Lipid-Lowering Activities of Cucurbitacins Isolated from Trichosanthes cucumeroides and Their Synthetic Derivatives

X Zhang, H Li, W Wang, T Chen… - Journal of Natural …, 2020 - ACS Publications
In the ongoing efforts to discover natural cholesterol-lowering compounds,
dihydrocucurbitacin B, isolated from Trichosanthes cucumeroides roots, was found to …

Collagen synthesis-promoting and collagenase inhibitory activities of constituents isolated from the rhizomes of Picrorhiza kurroa Royle ex Benth

T Morikawa, N Inoue, Y Nakanishi, Y Manse… - Fitoterapia, 2020 - Elsevier
Three new acylated phenylethanoid glycosides, kurroaosides A (14), B (15), and C (16), and
a new acylated cucurbitane-type triterpene glycoside, kurroaoside D (17), were isolated from …

Bryonia dioica aqueous extract induces apoptosis and G2/M cell cycle arrest in MDA‑MB 231 breast cancer cells

B Benarba, A Elmallah… - Molecular Medicine …, 2019 - spandidos-publications.com
Bryonia dioica Jacq. is a climbing perennial herb with tuberous roots which is widely used in
traditional medicine in Algeria for the treatment of cancer. The present study aimed to …

Cucurbitane Glucosides from the Root of Machilus yaoshansis

M Gan, M Liu, B Liu, S Lin, Y Zhang, J Zi… - Journal of natural …, 2011 - ACS Publications
Seven new cucurbitane triterpene glucosides (1–5, 8, and 9) and five known analogues (6,
7, 10, cucurbitacin I 2-O-β-d-glucopyranoside, and khekadaengoside K) have been isolated …

The antinociceptive effects of hydroalcoholic extract of Bryonia dioica in male rats

M Zarei, S Mohammadi, N Abolhassani, NM ASGARI - 2015 - sid.ir
Background: Side effects of synthetic analgesic drugs in the clinical practice have drawn
researchers' attention on developing the herbal medicine as more appropriate analgesic …