Using genetics for social science
KP Harden, PD Koellinger - Nature human behaviour, 2020 - nature.com
Social science genetics is concerned with understanding whether, how and why genetic
differences between human beings are linked to differences in behaviours and …
differences between human beings are linked to differences in behaviours and …
Advanced paternal age effects in neurodevelopmental disorders—review of potential underlying mechanisms
Multiple epidemiological studies suggest a relationship between advanced paternal age
(APA) at conception and adverse neurodevelopmental outcomes in offspring, particularly …
(APA) at conception and adverse neurodevelopmental outcomes in offspring, particularly …
Estimation of genetic correlation via linkage disequilibrium score regression and genomic restricted maximum likelihood
Genetic correlation is a key population parameter that describes the shared genetic
architecture of complex traits and diseases. It can be estimated by current state-of-art …
architecture of complex traits and diseases. It can be estimated by current state-of-art …
Genome-wide analysis identifies 12 loci influencing human reproductive behavior
The genetic architecture of human reproductive behavior—age at first birth (AFB) and
number of children ever born (NEB)—has a strong relationship with fitness, human …
number of children ever born (NEB)—has a strong relationship with fitness, human …
Hidden heritability due to heterogeneity across seven populations
Meta-analyses of genome-wide association studies, which dominate genetic discovery, are
based on data from diverse historical time periods and populations. Genetic scores derived …
based on data from diverse historical time periods and populations. Genetic scores derived …
Paternal age and psychiatric disorders: A review
H de Kluiver, JE Buizer‐Voskamp… - American Journal of …, 2017 - Wiley Online Library
We review the hypotheses concerning the association between the paternal age at
childbearing and childhood psychiatric disorders (autism spectrum‐and attention …
childbearing and childhood psychiatric disorders (autism spectrum‐and attention …
Risk of psychiatric illness from advanced paternal age is not predominantly from de novo mutations
The offspring of older fathers have higher risk of psychiatric disorders such as schizophrenia
and autism. Paternal-age-related de novo mutations are widely assumed to be the …
and autism. Paternal-age-related de novo mutations are widely assumed to be the …
Paternal-age-related de novo mutations and risk for five disorders
There are established associations between advanced paternal age and offspring risk for
psychiatric and developmental disorders. These are commonly attributed to genetic …
psychiatric and developmental disorders. These are commonly attributed to genetic …
The role of genetic liability in the association of urbanicity at birth and during upbringing with schizophrenia in Denmark
D Paksarian, BB Trabjerg, KR Merikangas… - Psychological …, 2018 - cambridge.org
BackgroundStudies have indicated that the association of urbanicity at birth and during
upbringing with schizophrenia may be driven by familial factors such as genetic liability. We …
upbringing with schizophrenia may be driven by familial factors such as genetic liability. We …
Advanced paternal age and risk of schizophrenia in offspring–review of epidemiological findings and potential mechanisms
A large number of studies have examined the association between advanced paternal age
(APA) and risk of schizophrenia in offspring. Here we present an overview of …
(APA) and risk of schizophrenia in offspring. Here we present an overview of …