Chemokines are a family of small, secreted cytokines which regulate a variety of cell
functions. The CXC motif chemokine ligand 12 (CXCL12) binds to CXC chemokine receptor …

Chemokines, small proinflammatory chemoattractant cytokines that bind to specific G-protein-
coupled seven-span transmembrane receptors, are major regulators of cell trafficking and …

Classical chemotherapeutic anti-cancer treatments induce cell death through DNA damage
by taking advantage of the proliferative behaviour of cancer cells. The more recent approach …

The mediators and cellular effectors of inflammation are important constituents of the local
environment of tumours. In some types of cancer, inflammatory conditions are present before …

Chemokines are 8–12 kDa peptides that function as chemoattractant cytokines and are
involved in cell activation, differentiation, and trafficking. Chemokines bind to specific G …

Inflammatory conditions in selected organs increase the risk of cancer. An inflammatory
component is present also in the microenvironment of tumours that are not epidemiologically …

Chemokines are small molecules called “chemotactic cytokines” and regulate many
processes like leukocyte trafficking, homing of immune cells, maturation, cytoskeletal …

Anaplastic thyroid cancer (ATC) is a rare malignancy. While external beam radiation therapy
has improved locoregional control, the median survival of∼ 4 months has not changed in …

The chemokine receptor CXCR4 belongs to the large superfamily of G-protein-coupled
receptors, and is directly involved in a number of biological processes including …

Sažetak Accumulating evidence shows that chronic inflammation is associated to increased
risk of cancer. An inflammatory component is present also in the microenvironment of …