Metabolic and biogeochemical consequences of viral infection in aquatic ecosystems

AE Zimmerman, C Howard-Varona… - Nature Reviews …, 2020 - nature.com
Ecosystems are controlled by 'bottom-up'(resources) and 'top-down'(predation) forces. Viral
infection is now recognized as a ubiquitous top-down control of microbial growth across …

Giant virus biology and diversity in the era of genome-resolved metagenomics

F Schulz, C Abergel, T Woyke - Nature Reviews Microbiology, 2022 - nature.com
The discovery of giant viruses, with capsids as large as some bacteria, megabase-range
genomes and a variety of traits typically found only in cellular organisms, was one of the …

[HTML][HTML] Personalized microbiome-driven effects of non-nutritive sweeteners on human glucose tolerance

J Suez, Y Cohen, R Valdés-Mas, U Mor… - Cell, 2022 - cell.com
Non-nutritive sweeteners (NNS) are commonly integrated into human diet and presumed to
be inert; however, animal studies suggest that they may impact the microbiome and …

AXL and error-prone DNA replication confer drug resistance and offer strategies to treat EGFR-mutant lung cancer

A Noronha, N Belugali Nataraj, JS Lee, B Zhitomirsky… - Cancer discovery, 2022 - AACR
Anticancer therapies have been limited by the emergence of mutations and other
adaptations. In bacteria, antibiotics activate the SOS response, which mobilizes error-prone …

Host succinate is an activation signal for Salmonella virulence during intracellular infection

G Rosenberg, D Yehezkel, D Hoffman, CC Mattioli… - Science, 2021 - science.org
Key to the success of intracellular pathogens is the ability to sense and respond to a
changing host cell environment. Macrophages exposed to microbial products undergo …

Algal blooms in the ocean: hot spots for chemically mediated microbial interactions

C Kuhlisch, A Shemi, N Barak-Gavish… - Nature Reviews …, 2024 - nature.com
The cycling of major nutrients in the ocean is affected by large-scale phytoplankton blooms,
which are hot spots of microbial life. Diverse microbial interactions regulate bloom dynamics …

Virocell metabolism: metabolic innovations during host–virus interactions in the ocean

S Rosenwasser, C Ziv, SG Van Creveld, A Vardi - Trends in microbiology, 2016 - cell.com
Marine viruses are considered to be major ecological, evolutionary, and biogeochemical
drivers of the marine environment, responsible for nutrient recycling and determining …

Lipid biomarkers for algal resistance to viral infection in the ocean

G Schleyer, C Kuhlisch, C Ziv… - Proceedings of the …, 2023 - National Acad Sciences
Marine viruses play a key role in regulating phytoplankton populations, greatly affecting the
biogeochemical cycling of major nutrients in the ocean. Resistance to viral infection has …

Potential auxiliary metabolic capabilities and activities reveal biochemical impacts of viruses in municipal wastewater treatment plants

L Yuan, F Ju - Environmental Science & Technology, 2023 - ACS Publications
Viruses influence biogeochemical cycles in oceans, freshwater, soil, and human gut through
infection and by modulating virocell metabolism through virus-encoded auxiliary metabolic …

[HTML][HTML] N-acetylneuraminic acid links immune exhaustion and accelerated memory deficit in diet-induced obese Alzheimer's disease mouse model

S Suzzi, T Croese, A Ravid, O Gold, AR Clark… - Nature …, 2023 - nature.com
Systemic immunity supports lifelong brain function. Obesity posits a chronic burden on
systemic immunity. Independently, obesity was shown as a risk factor for Alzheimer's …