[HTML][HTML] The Fetal Alcohol Spectrum Disorders—An Overview of Experimental Models, Therapeutic Strategies, and Future Research Directions

M Król, P Skowron, K Skowron, K Gil - Children, 2024 - mdpi.com
Since the establishment of a clear link between maternal alcohol consumption during
pregnancy and certain birth defects, the research into the treatment of FASD has become …

Anti-inflammatory, antioxidant, and antiapoptotic action of metformin attenuates ethanol neurotoxicity in the animal model of fetal alcohol spectrum disorders

M Sabzali, A Eidi, M Khaksari, H Khastar - Neurotoxicity Research, 2022 - Springer
Fetal alcohol exposure has permanent effects on the brain structure, leading to functional
deficits in several aspects of behavior, including learning and memory. Alcohol-induced …

[HTML][HTML] Novel Interventions on Comorbidities in Patients with Fetal Alcohol Spectrum Disorder (FASD): An Integrative Review

V Andreu-Fernández, N La Maida, M Marquina… - Biomedicines, 2024 - mdpi.com
Prenatal exposure to alcohol can cause Fetal Alcohol Spectrum Disorders (FASDs) after
birth, encompassing a spectrum of physical, cognitive, and behavioral abnormalities. FASD …

Interaction effect of crocin and citalopram on memory and locomotor activity in rats: An insight into BDNF and synaptophysin levels in the hippocampus

S Nasseri, S Hajrasouliha, S Vaseghi… - Naunyn-Schmiedeberg's …, 2024 - Springer
Selective serotonin reuptake inhibitors (SSRIs) are widely used drugs for the treatment of
depression. Citalopram is one of the most prescribed SSRIs that is useful for the treatment of …

Feeding crocin ameliorate cognitive dysfunction, oxidative stress and neuroinflammation induced by unpredictable chronic mild stress in rats

A Abbaszade-Cheragheali, S Kakhki, SR Khatibi… - …, 2023 - Springer
Introduction The aim of the current study was to investigate the probable mechanism and
effect of crocin on brain oxidative damage and memory deficits induced by unpredictable …

Converging mechanisms in ethanol neurotoxicity

MB Virgolini, RM Pautassi - Advances in Neurotoxicology, 2022 - Elsevier
Alcohol use disorder is a condition in which the individual keeps drinking alcohol despite
repeated attempts to stop or control such behavior, which in turn generates negative social …

The effect of crocin on cholestasis-induced spatial memory impairment with respect to the expression level of TFAM and PGC-1α and activity of catalase and …

S Mehrabanifar, S Hesami-Tackallou, S Vaseghi… - Metabolic Brain …, 2023 - Springer
Large evidence has shown that cholestasis has a wide-range of deleterious effects on brain
function, and also, on neurocognitive functions including learning and memory. On the other …

[HTML][HTML] Delay in the fine-tuning of locomotion in infants with meconium positive to biomarkers of alcohol exposure: a pilot study

G Coriale, M Ceccanti, M Fiore, F Tarani… - Rivista di …, 2024 - rivistadipsichiatria.it
Introduction. Prenatal alcohol exposure causes a variety of impairments to the fetus called
Fetal Alcohol Spectrum Disorders (FASD). Since it is very difficult to identify women that …

Crocin, a bioactive constituent of Crocus sativus, alleviates trimethyltin-induced cognitive deficits through down-regulation of hippocampal apoptosis and oxidative …

S Ghofrani, MT Joghataei… - Journal of Basic …, 2022 - journals.shahed.ac.ir
Background and Objective: Cognitive deficits are associated with neurodegenerative
disorders including Alzheimer's disease (AD). Trimethyltin chloride (TMT) with potent …

[PDF][PDF] Investigating the Relationship between Hippocampal BDNF Gene Expression and Spatial Memory in the Open Field Test in Offspring Born from Rats Treated …

MS Ghahremanlo, V Hojati, G Vaezi… - Journal of Chemical …, 2024 - journals.iau.ir
Alcohol consumption during pregnancy causes damage to the mother and the developing
fetus, especially the central nervous system. Exposure of pregnant mothers to ethanol …