Peptide-based vaccines for tuberculosis

W Gong, C Pan, P Cheng, J Wang, G Zhao… - Frontiers in …, 2022 - frontiersin.org
Tuberculosis (TB) is an infectious disease caused by Mycobacterium tuberculosis. As a
result of the coronavirus disease 2019 (COVID-19) pandemic, the global TB mortality rate in …

Designer outer membrane vesicles as immunomodulatory systems–reprogramming bacteria for vaccine delivery

YMD Gnopo, HC Watkins, TC Stevenson… - Advanced Drug Delivery …, 2017 - Elsevier
Vaccines often require adjuvants to be effective. Traditional adjuvants, like alum, activate the
immune response but in an uncontrolled way. Newer adjuvants help to direct the immune …

Bacterial components as naturally inspired nano-carriers for drug/gene delivery and immunization: Set the bugs to work?

F Farjadian, M Moghoofei, S Mirkiani, A Ghasemi… - Biotechnology …, 2018 - Elsevier
Drug delivery is a rapidly growing area of research motivated by the nanotechnology
revolution, the ideal of personalized medicine, and the desire to reduce the side effects of …

Treatment Strategies for Infections With Shiga Toxin-Producing Escherichia coli

S Mühlen, P Dersch - Frontiers in cellular and infection microbiology, 2020 - frontiersin.org
Infections with Shiga toxin-producing Escherichia coli (STEC) cause outbreaks of severe
diarrheal disease in children and the elderly around the world. The severe complications …

A review on strategies for decreasing E. ácoli O157: H7 risk in animals

P Saeedi, M Yazdanparast, E Behzadi… - Microbial …, 2017 - Elsevier
Enterohemorrhagic Escherichia coli (EHEC) serotype O157: H7 is a food-borne pathogen
that younger children are most prone to this microorganism. Hemolytic Uremic Syndrome …

[HTML][HTML] Prophylactic vaccine delivery systems against epidemic infectious diseases

C Pan, H Yue, L Zhu, G Ma, H Wang - Advanced drug delivery reviews, 2021 - Elsevier
Prophylactic vaccines have evolved from traditional whole-cell vaccines to safer subunit
vaccines. However, subunit vaccines still face problems, such as poor immunogenicity and …

Lipopolysaccharide structure impacts the entry kinetics of bacterial outer membrane vesicles into host cells

EJ O'Donoghue, N Sirisaengtaksin, DF Browning… - PLoS …, 2017 - journals.plos.org
Outer membrane vesicles are nano-sized microvesicles shed from the outer membrane of
Gram-negative bacteria and play important roles in immune priming and disease …

Approaches to treatment of emerging Shiga toxin-producing Escherichia coli infections highlighting the O104:H4 serotype

EA Rahal, SM Fadlallah, FJ Nassar, N Kazzi… - Frontiers in cellular …, 2015 - frontiersin.org
Shiga toxin-producing Escherichia coli (STEC) are a group of diarrheagenic bacteria
associated with foodborne outbreaks. Infection with these agents may result in grave …

Comparison of intranasal outer membrane vesicles with cholera toxin and injected MF59C. 1 as adjuvants for malaria transmission blocking antigens AnAPN1 and …

M Pritsch, N Ben-Khaled, M Chaloupka… - Journal of …, 2016 - Wiley Online Library
Purified protein vaccines often require adjuvants for efficient stimulation of immune
responses. There is no licensed mucosal adjuvant on the market to adequately boost the …

Characterization and Food Application of the Novel Lytic Phage BECP10: Specifically Recognizes the O-polysaccharide of Escherichia coli O157:H7

DW Park, JH Park - Viruses, 2021 - mdpi.com
Escherichia coli O157: H7 is a global concern that causes serious diseases, such as
hemolytic uremic syndrome and bloody diarrhea. To control E. coli O157: H7 in food, a novel …