In addition to its antioxidative effects melatonin acts through specific nuclear and plasma
membrane receptors. To date, two G-protein coupled melatonin membrane receptors, MT1 …

The purpose of this systematic review is to access the current state of knowledge concerning
the role for melatonin in human pregnancy. Melatonin is a neuroendocrine hormone …

The systemic administration of a potent muscarinic agonist pilocarpine in rats promotes
sequential behavioral and electrographic changes that can be divided into 3 distinct …

Neuroprotection is increasingly considered as a promising therapy for preventing and
treating temporal lobe epilepsy (TLE). The development of chronic TLE, also termed as …

Epilepsy is known as one of the most frequent neurological diseases, characterized by an
enduring predisposition to generate epileptic seizures. Oxidative stress is believed to …

Epilepsy is thought to be associated with oxidative stress, glutamate excitotoxicity, and
mitochondrial dysfunction. The enhanced synthesis and release of oxygen free radicals is …

Background: Neuronal hyperexcitability and excessive production of free radicals have been
implicated in the pathogenesis of a considerable range of neurological disorders, including …

A large body of experimental and clinical evidence has strongly suggested that monoamines
play an important role in regulating epileptogenesis, seizure susceptibility, convulsions, and …

Accumulating evidence indicates an interaction between inflammation and depression since
increased levels of pro-inflammatory cytokines are associated with depression-related …

Epilepsy is a chronic brain disease that affects approximately 65 million people worldwide.
However, despite the continuous development of antiepileptic drugs, over 30% patients with …