Fungi are eukaryotic microorganisms found in nature, which can invade the human body
and cause tissue damage, inflammatory reactions, organ dysfunctions, and diseases. These …

Fungal infections represent a major, albeit neglected, public health threat with serious
medical and economic burdens globally. With unacceptably high mortality rates, invasive …

Extracellular vesicles (EVs) are nanoparticles containing various bioactive cargos—eg,
proteins, RNAs, and lipids—that are released into the environment by all cell types. They are …

Human fungal pathogens are a deadly and underappreciated risk to global health that most
severely affect immunocompromised individuals. A virulence attribute shared by some of the …

The fungus Cryptococcus neoformans is a major human pathogen with a remarkable
intracellular survival strategy that includes exiting macrophages through non-lytic exocytosis …

As healthcare improves and our ability to support patients with compromised immune
systems increases, such patients become more vulnerable to microbes in the environment …

Cryptococcus neoformans is a lethal fungus that primarily affects the respiratory system and
the central nervous system. One of the main virulence factors is the capsule, constituted by …

Fungal infections kill close to 3.8 million people yearly, with the biggest burden in resource-
limited regions. One of the leading causes of fungal infections is the environmental …

Gene knockout strain collections are important tools for discovery in microbiology. The only
available genome-wide deletion collection for a human pathogenic fungus, Cryptococcus …