The measurement of vascular function in isolated vessels has revealed important insights
into the structural, functional, and biomechanical features of the normal and diseased …

Of the 21 members of the connexin family, 4 (Cx37, Cx40, Cx43, and Cx45) are expressed in
the endothelium and/or smooth muscle of intact blood vessels to a variable and dynamically …

Biological tissues are fed by arterial networks whose task is to set blood flow delivery in
accordance with energetic demand. Coordinating vasomotor activity among hundreds of …

Rationale: Increasing prevalence of obesity and its associated risk with cardiovascular
diseases demands a better understanding of the contribution of different cell types within this …

Globin proteins exist in every cell type of the vasculature, from erythrocytes to endothelial
cells, vascular smooth muscle cells, and peripheral nerve cells. Many globin subtypes are …

Key points Endothelial cell TRPV4 (TRPV4EC) channels exert a dilatory effect on the resting
diameter of resistance mesenteric and pulmonary arteries. Functional intermediate‐and …

Obstructive sleep apnea is a chronic and prevalent condition that is associated with
endothelial dysfunction, atherosclerosis, and imposes excess overall cardiovascular risk …

The endothelium controls vascular tone adopting blood flow to tissue needs. It releases
chemical mediators [eg, nitric oxide (NO), prostaglandins (PG)] and exerts appreciable …

Endothelium-derived hyperpolarizing factor (EDHF) was envisaged as a chemical entity
causing vasodilation by hyperpolarizing vascular smooth muscle (VSM) cells and distinct …

A monolayer of endothelial cells lines the innermost surface of all blood vessels, thereby
coming into close contact with every region of the body and perceiving signals deriving from …