Alcohol-Associated Hepatitis | New England Journal of Medicine Skip to main content The New
England Journal of Medicine homepage Advanced Search SEARCH SPECIALTIES Cardiology …

As an evolutionarily conserved signalling network, the Hippo pathway plays a crucial role in
the regulation of numerous biological processes. Thus, substantial efforts have been made …

Alcohol-associated liver disease (ALD) is a major cause of chronic liver disease worldwide,
and comprises a spectrum of several different disorders, including simple steatosis …

Adult hepatocyte identity is constructed throughout embryonic development and fine-tuned
after birth. A multinodular network of transcription factors, along with pre-mRNA splicing …

Accumulating evidence shows widespread contamination of water sources and food with
microplastics. Although the liver is one of the main sites of bioaccumulation within the …

Dysfunctional mitochondria are removed via multiple pathways, such as mitophagy, a
selective autophagy process. Here, we identify an intracellular hybrid mitochondria …

Alcohol-associated liver disease (ALD) is one of the major diseases arising from chronic
alcohol consumption and is one of the most common causes of liver-related morbidity and …

The liver is known as an organ with high proliferation potential. Clarifying the cellular origin
and deepening the understanding of liver regeneration mechanisms will help provide new …

Tissue injury triggers activation of mesenchymal lineage cells into wound-repairing
myofibroblasts, whose unrestrained activity leads to fibrosis. Although this process is largely …

The large and growing burden of alcohol-associated liver disease—and the considerable
burden of morbidity and mortality associated with it—has been a drive toward ongoing …