Here, we addressed the pharmacology and toxicology of synthetic organoselenium
compounds and some naturally occurring organoselenium amino acids. The use of …

Since the discovery of long-term potentiation (LTP) in 1973, thousands of papers have been
published on this intriguing phenomenon, which provides a compelling cellular model for …

Interest in excitotoxicity expanded following its implication in the pathogenesis of ischemic
brain injury in the 1980s, but waned subsequent to the failure of N-methyl-D-aspartate …

The analysis of the contributions to synaptic plasticity and memory of cAMP, PKA, CRE,
CREB-1, CREB-2, and CPEB has recruited the efforts of many laboratories all over the …

Glutamate is one of the most prominent neurotransmitter in the body, present in over 50% of
nervous tissue and plays an important role in neuronal excitation. This neuronal excitation is …

The synapse is the functional unit of the brain. During the last several decades we have
acquired a great deal of information on its structure, molecular components, and …

This brief review article makes the argument that glutamate is deserving of its newfound
attention within the neuroscience literature and that many directions of important research …

We hypothesized that bone evolved, in part, to enhance the ability of bony vertebrates to
escape danger in the wild. In support of this notion, we show here that a bone-derived signal …

Despite the ongoing fundamental controversy about the physiological function of sleep,
there is general consensus that sleep benefits neuronal plasticity, which ultimately supports …

Glutamate occupies a central position in amino acid metabolism in plants. The acidic amino
acid is formed by the action of glutamate synthase, utilizing glutamine and 2-oxoglutarate …