Approaches for bacteriophage genome engineering
M Mahler, AR Costa, SPB van Beljouw… - Trends in …, 2023 - cell.com
In recent years, bacteriophage research has been boosted by a rising interest in using
phage therapy to treat antibiotic-resistant bacterial infections. In addition, there is a desire to …
phage therapy to treat antibiotic-resistant bacterial infections. In addition, there is a desire to …
Engineering bacteriophages as versatile biologics
S Kilcher, MJ Loessner - Trends in microbiology, 2019 - cell.com
Viruses of bacteria (bacteriophages or phages) are highly evolved nanomachines that
recognize bacterial cell walls, deliver genetic information, and kill or transform their targets …
recognize bacterial cell walls, deliver genetic information, and kill or transform their targets …
Reporter phage-based detection of bacterial pathogens: design guidelines and recent developments
Fast and reliable detection of bacterial pathogens in clinical samples, contaminated food
products, and water supplies can drastically improve clinical outcomes and reduce the socio …
products, and water supplies can drastically improve clinical outcomes and reduce the socio …
Emerging investigator series: bacteriophages as nano engineering tools for quality monitoring and pathogen detection in water and wastewater
Waterborne bacterial pathogens are a major public health concern worldwide, taking many
lives and imposing huge economical burden. Rapid and specific detection of pathogens and …
lives and imposing huge economical burden. Rapid and specific detection of pathogens and …
Approaches to optimize therapeutic bacteriophage and bacteriophage-derived products to combat bacterial infections
M Reuter, DH Kruger - Virus Genes, 2020 - Springer
The emerging occurrence of antibiotic-resistant bacterial pathogens leads to a recollection
of bacteriophage as antimicrobial therapeutics. This article presents a short overview of the …
of bacteriophage as antimicrobial therapeutics. This article presents a short overview of the …
Genetic engineering and biosynthesis technology: Keys to unlocking the chains of phage therapy
S Lv, Y Wang, K Jiang, X Guo, J Zhang, F Zhou, Q Li… - Viruses, 2023 - mdpi.com
Phages possess the ability to selectively eliminate pathogenic bacteria by recognizing
bacterial surface receptors. Since their discovery, phages have been recognized for their …
bacterial surface receptors. Since their discovery, phages have been recognized for their …
Selective killing of pathogenic bacteria by antimicrobial silver nanoparticle—Cell wall binding domain conjugates
Broad-spectrum antibiotics indiscriminately kill bacteria, removing nonpathogenic
microorganisms and leading to evolution of antibiotic resistant strains. Specific …
microorganisms and leading to evolution of antibiotic resistant strains. Specific …
Recombinant Reporter Phage rTUN1::nLuc Enables Rapid Detection and Real-Time Antibiotic Susceptibility Testing of Klebsiella pneumoniae K64 Strains
The emergence of multi-drug-resistant Klebsiella pneumoniae (Kp) strains constitutes an
enormous threat to global health as multi-drug resistance-associated treatment failure …
enormous threat to global health as multi-drug resistance-associated treatment failure …
Three Novel Bacteriophages, J5a, F16Ba, and z1a, Specific for Bacillus anthracis, Define a New Clade of Historical Wbeta Phage Relatives
A Nakonieczna, P Rutyna, M Fedorowicz, M Kwiatek… - Viruses, 2022 - mdpi.com
Bacillus anthracis is a potent biowarfare agent, able to be highly lethal. The bacteria dwell in
the soil of certain regions, as natural flora. Bacteriophages or their lytic enzymes, endolysins …
the soil of certain regions, as natural flora. Bacteriophages or their lytic enzymes, endolysins …
A Syringe-Based Biosensor to Rapidly Detect Low Levels of Escherichia coli (ECOR13) in Drinking Water Using Engineered Bacteriophages
A sanitized drinking water supply is an unconditional requirement for public health and the
overall prosperity of humanity. Potential microbial and chemical contaminants of drinking …
overall prosperity of humanity. Potential microbial and chemical contaminants of drinking …